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Small Nuclear RNA Activating Complex Recombinant Protein | SNAPC1 recombinant protein

Recombinant Human Small Nuclear RNA Activating Complex, Polypeptide 1

Gene Names
SNAPC1; SNAP43; PTFgamma
Purity
Greater than 80.0% as determined by SDS-PAGE.
Synonyms
Small Nuclear RNA Activating Complex; Recombinant Human Small Nuclear RNA Activating Complex; Polypeptide 1; SNAPC1 Human; Polypeptide 1 Human Recombinant; PTFgamma; SNAP43; snRNA-activating protein complex subunit 1; SNAPc subunit 1; Proximal sequence element-binding transcription factor subunit gamma; PSE-binding factor subunit gamma; PTF subunit gamma; Small nuclear RNA-activating complex polypeptide 1; SNAPc 43 kDa subunit; SNAPC1; SNAPC1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 80.0% as determined by SDS-PAGE.
Form/Format
SNAPC1 protein solution (1mg/ml) contains 20mM Tris-HCl (pH 8.0) and 10% glycerol.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMGTPPGL QTDCEALLSR FQETDSVRFE DFTELWRNMK FGTIFCGRMRNLEKNMFTKE ALALAWRYFL PPYTFQIRVG ALYLLYGLYN TQLCQPKQKI RVALKDWDEV LKFQQDLVNAQHFDAAYIFR KLRLDRAFHF TAMPKLLSYR MKKKIHRAEV TEEFKDPSDR VMKLITSDVL EEMLNVHDHYQNMKHVISVD KSKPDKALSL IKDDFFDNIK NIVLEHQQWH KDRKNPSLKS KTNDGEEKME GNSQETERCERAESLAKIKS KAFSVVIQAS KSRRHRQVKL DSSDSDSASG QGQVKATRKK EKKERLKPAG RKMSLRNKGNVQNIHKEDKP LSLSMPVITE EEENESLSGT EFTASKKRRK H
Sequence Length
368
Related Product Information for SNAPC1 recombinant protein
Introduction: Small Nuclear RNA Activating Complex, Polypeptide 1 (SNAPC1) is a part of the SNAPc complex necessary for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC1 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Moreover, SNAPC1 recruits TBP and BRF2 to the U6 snRNA TATA box.

Description: SNAPC1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 391 amino acids (1-368 a.a) and having a molecular mass of 45.4kDa.SNAPC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for SNAPC1 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,994 Da
NCBI Official Full Name
snRNA-activating protein complex subunit 1
NCBI Official Synonym Full Names
small nuclear RNA activating complex polypeptide 1
NCBI Official Symbol
SNAPC1
NCBI Official Synonym Symbols
SNAP43; PTFgamma
NCBI Protein Information
snRNA-activating protein complex subunit 1
UniProt Protein Name
snRNA-activating protein complex subunit 1
UniProt Gene Name
SNAPC1
UniProt Synonym Gene Names
SNAP43; SNAPc subunit 1; PSE-binding factor subunit gamma; PTF subunit gamma; SNAPc 43 kDa subunit
UniProt Entry Name
SNPC1_HUMAN

Uniprot Description

SNAPC1: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

Chromosomal Location of Human Ortholog: 14q22

Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus; snRNA-activating protein complex

Molecular Function: sequence-specific DNA binding

Biological Process: snRNA transcription from RNA polymerase II promoter; snRNA transcription from RNA polymerase III promoter

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Product Notes

The SNAPC1 snapc1 (Catalog #AAA140750) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMGT PPGL QTDCEALLSR FQETDSVRFE DFTELWRNMK FGTIFCGRMR NLEKNMFTKE ALALAWRYFL PPYTFQIRVG ALYLLYGLYN TQLCQPKQKI RVALKDWDEV LKFQQDLVNA QHFDAAYIFR KLRLDRAFHF TAMPKLLSYR MKKKIHRAEV TEEFKDPSDR VMKLITSDVL EEMLNVHDHY QNMKHVISVD KSKPDKALSL IKDDFFDNIK NIVLEHQQWH KDRKNPSLKS KTNDGEEKME GNSQETERCE RAESLAKIKS KAFSVVIQAS KSRRHRQVKL DSSDSDSASG QGQVKATRKK EKKERLKPAG RKMSLRNKGN VQNIHKEDKP LSLSMPVITE EEENESLSGT EFTASKKRRK H. It is sometimes possible for the material contained within the vial of "Small Nuclear RNA Activating Complex, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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