Mouse snail homolog 1 (Drosophila) ELISA Kit | SNAI1 elisa kit
Mouse Zinc finger protein SNAI1, SNAI1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Snail1: a protein of the C2H2-type zinc-finger family that regulates transcription. Involved in embryonic mesoderm formation. Plays a role in the epithelial to mesenchymal transition (EMT). EMT is characterized by decreased levels of the epithelial markers E-cadherin and alpha- and beta-catenin, and increased cellular migration and expression of the mesenchymal markers fibronectin, vimentin, N-cadherin and smooth muscle alpha-actin.E Snail binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. NF-kappaB binds and regulates the snail promoter and is critical for EMT, and inhibition of NF-kappaB activity lowered snail levels and morphologically reversed the EMT.
Protein type: C2H2-type zinc finger protein; Transcription factor
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; nucleic acid binding; DNA binding; sequence-specific DNA binding; metal ion binding; transcription factor activity; kinase binding
Biological Process: transcription from RNA polymerase II promoter; cell migration; hair follicle morphogenesis; positive regulation of transcription, DNA-dependent; multicellular organismal development; palate development; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; negative regulation of DNA damage response, signal transduction by p53 class mediator; mesoderm formation; epithelial to mesenchymal transition; mesoderm development; negative regulation of transcription, DNA-dependent; positive regulation of cell migration
Research Articles on SNAI1
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Product Notes
The Mouse SNAI1 snai1 (Catalog #AAA9343377) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9343377 ELISA Kit recognizes Mouse SNAI1. It is sometimes possible for the material contained within the vial of "snail homolog 1 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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