Mouse Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) ELISA Kit | SMG6 elisa kit
Mouse Telomerase-binding protein EST1A, SMG6 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
EST1A: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'- (GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER). 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus; Hydrolase; EC 3.1.-.-; DNA-binding
Cellular Component: chromosome, telomeric region; cytoplasm; nucleolus; chromosome; cytosol; nucleus
Molecular Function: endoribonuclease activity; nuclease activity; DNA binding; hydrolase activity; endonuclease activity; metal ion binding; telomeric DNA binding; T/G mismatch-specific endonuclease activity; phosphoric ester hydrolase activity
Biological Process: mRNA catabolic process, nonsense-mediated decay; telomere maintenance
Similar Products
Product Notes
The Mouse SMG6 smg6 (Catalog #AAA9327559) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9327559 ELISA Kit recognizes Mouse SMG6. It is sometimes possible for the material contained within the vial of "Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
