Sperm Mitochondria-Associated Cysteine-Rich Recombinant Protein | SMCP recombinant protein
Recombinant Human Sperm Mitochondria-Associated Cysteine-Rich Protein
Gene Names
SMCP; MCS; MCSP; HSMCSGEN1
Purity
Greater than 85.0% as determined by SDS-PAGE.
Synonyms
Sperm Mitochondria-Associated Cysteine-Rich; Recombinant Human Sperm Mitochondria-Associated Cysteine-Rich Protein; SMCP Human; Sperm Mitochondria-Associated Cysteine-Rich Protein Human Recombinant; Sperm Mitochondria-Associated Cysteine-Rich Protein; MCSP; MCS; Mitochondrial Capsule Selenoprotein; HSMCSGEN1; Sperm Mitochondrial-Associated Cysteine-Rich Protein; SMCP recombinant protein
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
SMCP protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol, 1mM EDTA and 0.1mM PMSF.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMCDQTKH SKCCPAKGNQ CCPPQQNQCC QSKGNQCCPP KQNQCCQPKG SQCCPPKHNH CCQPKPPCCI QARCCGLETK PEVSPLNMES EPNSPQTQDK GCQTQQQPHS PQNESRPSK
Sequence Length
116
Related Product Information for SMCP recombinant protein
Description: SMCP Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 139 amino acids (1-116 a.a) and having a molecular mass of 15.2kDa (Molecular size on SDS-PAGE will appear higher). SMCP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: SMCP is a protein-coding gene. SMCP localizes to the capsule linked with the mitochondrial outer membranes and assumed to function in the organization and stabilization of the helical structure of the sperm's mitochondrial sheath. Sperm mitochondria vary in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially construct a helical coiled sheath in the midpiece of the sperm flagellum. Diseases associated with SMCP include middle ear disease, and hard palate cancer.
Introduction: SMCP is a protein-coding gene. SMCP localizes to the capsule linked with the mitochondrial outer membranes and assumed to function in the organization and stabilization of the helical structure of the sperm's mitochondrial sheath. Sperm mitochondria vary in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially construct a helical coiled sheath in the midpiece of the sperm flagellum. Diseases associated with SMCP include middle ear disease, and hard palate cancer.
Product Categories/Family for SMCP recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12,767 Da
NCBI Official Full Name
sperm mitochondrial-associated cysteine-rich protein
NCBI Official Synonym Full Names
sperm mitochondria-associated cysteine-rich protein
NCBI Official Symbol
SMCP
NCBI Official Synonym Symbols
MCS; MCSP; HSMCSGEN1
NCBI Protein Information
sperm mitochondrial-associated cysteine-rich protein; mitochondrial capsule selenoprotein
UniProt Protein Name
Sperm mitochondrial-associated cysteine-rich protein
Protein Family
UniProt Gene Name
SMCP
UniProt Synonym Gene Names
MCS; MCSP
UniProt Entry Name
MCSP_HUMAN
NCBI Description
Sperm mitochondria differ in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially to form a helical coiled sheath in the midpiece of the sperm flagellum. The protein encoded by this gene localizes to the capsule associated with the mitochondrial outer membranes and is thought to function in the organization and stabilization of the helical structure of the sperm's mitochondrial sheath. [provided by RefSeq, Jul 2008]
Uniprot Description
SMCP: Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida.
Chromosomal Location of Human Ortholog: 1q21.3
Cellular Component: mitochondrion; mitochondrial membrane; cytoplasm
Biological Process: sperm motility; penetration of zona pellucida
Research Articles on SMCP
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Product Notes
The SMCP smcp (Catalog #AAA145721) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMCD QTKH SKCCPAKGNQ CCPPQQNQCC QSKGNQCCPP KQNQCCQPKG SQCCPPKHNH CCQPKPPCCI QARCCGLETK PEVSPLNMES EPNSPQTQDK GCQTQQQPHS PQNESRPSK. It is sometimes possible for the material contained within the vial of "Sperm Mitochondria-Associated Cysteine-Rich, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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