Mouse structural maintenance of chromosomes 6 ELISA Kit | SMC6 elisa kit
Mouse Structural maintenance of chromosomes protein 6, SMC6 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SMC6L1: Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. Belongs to the SMC family. SMC6 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA repair, damage
Cellular Component: nucleoplasm; PML body; chromosome, telomeric region; nucleolus; intracellular; chromosome; nucleus
Molecular Function: nucleotide binding; ATP binding
Biological Process: telomere maintenance via recombination; DNA repair; response to DNA damage stimulus; double-strand break repair via homologous recombination; DNA recombination
Research Articles on SMC6
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Product Notes
The Mouse SMC6 smc6 (Catalog #AAA9318732) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318732 ELISA Kit recognizes Mouse SMC6. It is sometimes possible for the material contained within the vial of "structural maintenance of chromosomes 6, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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