Serotonin Transporter (SERT) Recombinant Protein | SERT recombinant protein
Recombinant Serotonin Transporter (SERT)
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
NCBI and Uniprot Product Information
Uniprot Description
SERT: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: cytosol; endomembrane system; endosome; integral to membrane; integral to plasma membrane; lipid raft; membrane; neuron projection; plasma membrane
Molecular Function: actin filament binding; cocaine binding; monoamine transmembrane transporter activity; myosin binding; neurotransmitter:sodium symporter activity; nitric-oxide synthase binding; protein binding; protein homodimerization activity; Rab GTPase binding; serotonin transmembrane transporter activity; serotonin:sodium symporter activity; symporter activity; syntaxin-1 binding
Biological Process: brain morphogenesis; circadian rhythm; memory; monoamine transport; negative regulation of granule cell precursor proliferation; negative regulation of neuron differentiation; negative regulation of organ growth; negative regulation of synaptic transmission, dopaminergic; neurotransmitter transport; positive regulation of cell cycle; protein homooligomerization; protein oligomerization; response to toxin; serotonin transport; serotonin uptake; social behavior; sperm ejaculation; synaptic transmission; thalamus development; transport; vasoconstriction
Research Articles on SERT
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Product Notes
The SERT slc6a4 (Catalog #AAA2124572) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Serotonin Transporter (SERT) can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the SERT slc6a4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Ser483~Val 630. It is sometimes possible for the material contained within the vial of "Serotonin Transporter (SERT), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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