Human solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter) , member D1 ELISA Kit | SLC35D1 elisa kit
Human UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, SLC35D1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia.[provided by RefSeq, Sep 2009]
Uniprot Description
SLC35D1: Transports both UDP-glucuronic acid (UDP-GlcA) and UDP- N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis. Defects in SLC35D1 are a cause of Schneckenbecken dysplasia (SCHBCKD). Schneckenbecken dysplagia is a rare, autosomal recessive, lethal short-limbed skeletal dysplasia with platyspondylia. Belongs to the TPT transporter family. SLC35D subfamily.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 1p31.3
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: UDP-glucuronic acid transmembrane transporter activity
Biological Process: UDP-glucuronic acid transport; chondroitin sulfate biosynthetic process; embryonic skeletal development; xenobiotic metabolic process; carbohydrate transport; UDP-glucuronate biosynthetic process; transmembrane transport
Disease: Schneckenbecken Dysplasia
Research Articles on SLC35D1
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Product Notes
The Human SLC35D1 slc35d1 (Catalog #AAA9319472) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319472 ELISA Kit recognizes Human SLC35D1. It is sometimes possible for the material contained within the vial of "solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter) , member D1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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