SLC2A3 recombinant protein

Recombinant Human SLC2A3 protein

Cat. Num. AAA1562752

• Gene Names: SLC2A3; GLUT3
• Purity: >90% as determined by SDS-PAGE
• Synonyms: SLC2A3; Recombinant Human SLC2A3 protein; Solute carrier family 2; facilitated glucose transporter member 3; Glucose transporter type 3;; brain; GLUT-3; SLC2A3 recombinant protein

• Host: E Coli
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized. Lyophilized from PBS pH 7.4, 0.2% NLS, 5% Trehalose, 5% Mannose, 1mM EDTA.

• Species: Homo sapiens (Human)
• Protein Construction: A DNA sequence encoding the human SLC2A3 (Glu207-Gln281) was fused with GST tag
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Preparation and Storage: Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.; In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Related Product Information for SLC2A3 recombinant protein

Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport.

Product Categories/Family for SLC2A3 recombinant protein

Protein

NCBI and Uniprot Product Information

• NCBI GI #: 5902090
• NCBI GeneID: 6515
• NCBI Accession #: NP_008862.1
• NCBI GenBank Nucleotide #: NM_006931.2
• UniProt Accession #: P11169; Q6I9U2; Q9UG15; B2R606; D3DUU6
• Molecular Weight: 53,924 Da
• NCBI Official Full Name: solute carrier family 2, facilitated glucose transporter member 3
• NCBI Official Synonym Full Names: solute carrier family 2 (facilitated glucose transporter), member 3
• NCBI Official Symbol: SLC2A3
• NCBI Official Synonym Symbols: GLUT3
• NCBI Protein Information: solute carrier family 2, facilitated glucose transporter member 3; GLUT-3; glucose transporter type 3, brain
• UniProt Protein Name: Solute carrier family 2, facilitated glucose transporter member 3
• Protein Family: Solute carrier family
• UniProt Gene Name: SLC2A3
• UniProt Synonym Gene Names: GLUT3; GLUT-3
• UniProt Entry Name: GTR3_HUMAN

Uniprot Description

GLUT3: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. It???s surface expression is induced by insulin. It is restricted in humans to brain, testis (in the spermatozoa), and skeletal muscle, mostly in triads of slow-twitch fibres. Detected only in the brain of mouse and rat. IHC demonstrates its present in neurons, mainly at the plasma membrane, and to a lesser extent on intracellular vesicles distinct from synaptic vesicles. Present in the a-granules of human platelets, where it is translocated to the cell surface in response to thrombin stimulation. Its surface expression is increased by insulin or insulin growth-factor in cultured L6 muscle cells.

Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function: glucose transmembrane transporter activity

Biological Process: vitamin metabolic process; hexose transport; carbohydrate metabolic process; L-ascorbic acid metabolic process; pathogenesis; glucose transport; transmembrane transport; water-soluble vitamin metabolic process