Glucose Transporter 14 (GLUT14) Recombinant Protein | GLUT14 recombinant protein

Recombinant Glucose Transporter 14 (GLUT14)

Cat. Num. AAA2009603

• Gene Names: SLC2A14; GLUT14; SLC2A3P3
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Glucose Transporter 14 (GLUT14); Recombinant Glucose Transporter 14 (GLUT14); GLUT14 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and S-tag, its sequence is listed below.; MHHHHHHSSG LVPRGSGMKE TAAAKFERQH MDSPDLGTDD DDKAMADIGS EF- P ESPRFLLINR KKEENATRIL QRLWGTQDVS QDIQEMKDES ARMSQEKQVT VLELFRVSSYRQP
• Sequence Length: 520

• Applicable Applications for GLUT14 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Homo sapiens (Human)
• Expression System: Prokaryotic expression
• Residues: Pro230~Pro293 (Accession # Q8TDB8) with two N-terminal Tags, His-tag and S-tag
• Subcellular Location: Membrane; Multi-pass membrane protein
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Predicted Isoelectric Point: 5.9
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 555943800
• NCBI GeneID: 144195
• NCBI Accession #: NP_001273162.1
• NCBI GenBank Nucleotide #: NM_001286233.1
• UniProt Accession #: Q8TDB8; Q6UY84; Q8TDB9; B3KVB5; B3KWW7
• Molecular Weight: 13.3kDa
• NCBI Official Full Name: solute carrier family 2, facilitated glucose transporter member 14 isoform a
• NCBI Official Synonym Full Names: solute carrier family 2 (facilitated glucose transporter), member 14
• NCBI Official Symbol: SLC2A14
• NCBI Official Synonym Symbols: GLUT14; SLC2A3P3
• NCBI Protein Information: solute carrier family 2, facilitated glucose transporter member 14; glucose transporter type 14; solute carrier family 2 (facilitated glucose transporter), member 3 pseudogene 3
• UniProt Protein Name: Solute carrier family 2, facilitated glucose transporter member 14
• UniProt Gene Name: SLC2A14
• UniProt Synonym Gene Names: GLUT14; GLUT3; GLUT-14
• UniProt Entry Name: GTR14_HUMAN

NCBI Description

Members of the glucose transporter (GLUT) family, including SLC2A14, are highly conserved integral membrane proteins that transport hexoses such as glucose and fructose into all mammalian cells. GLUTs show tissue and cell-type specific expression (Wu and Freeze, 2002 [PubMed 12504846]).[supplied by OMIM, Mar 2008]

Uniprot Description

SLC2A14: Facilitative glucose transporter. May have a specific function related to spermatogenesis. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 12p13.31

Cellular Component: integral to membrane; nucleus

Molecular Function: glucose transmembrane transporter activity

Biological Process: multicellular organismal development; spermatogenesis; glucose transport; cell differentiation; transmembrane transport