Rat solute carrier family 22, member 17 ELISA Kit | SLC22A17 elisa kit
Rat Solute carrier family 22 member 17, SLC22A17 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
may act as a brain-specific organic ion transporter [RGD, Feb 2006]
Uniprot Description
SLC22A17: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family; Transporter
Cellular Component: cell; integral to plasma membrane; vacuolar membrane
Molecular Function: transmembrane receptor activity; transmembrane transporter activity
Biological Process: iron ion homeostasis; siderophore transport; ion transport; signal transduction; transmembrane transport
Research Articles on SLC22A17
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Product Notes
The Rat SLC22A17 slc22a17 (Catalog #AAA9330092) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9330092 ELISA Kit recognizes Rat SLC22A17. It is sometimes possible for the material contained within the vial of "solute carrier family 22, member 17, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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