Gibbon Ape Leukemia Virus Receptor 1 Recombinant Protein | GLVR1 recombinant protein

Recombinant Gibbon Ape Leukemia Virus Receptor 1 (GLVR1)

Cat. Num. AAA2034605

• Reactivity: Mouse
• Applications: ELISA, Immunoprecipitation, SDS-Page, Western Blot
• Purity: > 90%
• Synonyms: Gibbon Ape Leukemia Virus Receptor 1; Recombinant Gibbon Ape Leukemia Virus Receptor 1 (GLVR1); Sodium-Dependent Phosphate Transporter 1; Solute Carrier Family 20 Member 1; Leukemia virus receptor 1 homolog; Phosphate transporter 1; GLVR1 recombinant protein

• Host: E Coli; Source: Prokaryotic expression
• Reactivity: Mouse
• Purity/Purification: > 90%
• Form/Format: Freeze-dried powder
• Sequence Length: 646

• Applicable Applications for GLVR1 recombinant protein: SDS-PAGE; Western Blot (WB); ELISA (EIA); Immunoprecipitation (IP)
• Usage: Reconstitute in PBS or others.
• Endotoxin Level: < 1.0EU per 1ug (determined by the LAL method)
• Buffer Formulation: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Fragment: Cys255~Ser515
• Tag: Two N-terminal Tags, His-tag and T7-tag
• Residues & Tags: Cys255~Ser515 with N-terminal His Tag
• Subcellular Location: Secreted
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 4416261
• Molecular Weight: Predicted: 33.0kDa
• NCBI Official Full Name: gibbon ape leukemia virus receptor 1, partial
• UniProt Protein Name: Sodium-dependent phosphate transporter 1
• UniProt Gene Name: SLC20A1
• UniProt Synonym Gene Names: GLVR1; PIT1; GLVR-1; PiT-1
• UniProt Entry Name: S20A1_HUMAN

Uniprot Description

SLC20A1: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV). Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.

Protein type: Membrane protein, multi-pass; Transporter; Transporter, SLC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q13

Cellular Component: integral to plasma membrane; membrane; plasma membrane

Molecular Function: inorganic phosphate transmembrane transporter activity; receptor activity; signal transducer activity; sodium-dependent phosphate transmembrane transporter activity; sodium:inorganic phosphate symporter activity; sodium:phosphate symporter activity

Biological Process: ion transport; phosphate metabolic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; transport