Rat Excitatory amino acid transporter 1 ELISA Kit | Slc1a3 elisa kit
Rat Excitatory amino acid transporter 1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
carries out Na+ dependent transport of glutamate and aspartate; may regulate neurotransmitter concentration in the central nervous system [RGD, Feb 2006]
Uniprot Description
SLC1A3: Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 2q16
Cellular Component: basolateral plasma membrane; cell projection; cell soma; cell surface; dendritic spine; integral to plasma membrane; mitochondrial inner membrane; neuron projection; plasma membrane; synapse
Molecular Function: acidic amino acid transmembrane transporter activity; amino acid binding; glutamate binding; glutamate:sodium symporter activity; high-affinity glutamate transmembrane transporter activity; L-glutamate transmembrane transporter activity
Biological Process: auditory behavior; cranial nerve development; gamma-aminobutyric acid biosynthetic process; glutamate biosynthetic process; glutamate metabolic process; L-glutamate import; L-glutamate transport; malate-aspartate shuttle; neuromuscular process controlling balance; neuron morphogenesis during differentiation; neurotransmitter transport; positive regulation of synaptic transmission; response to antibiotic; response to drug; response to inorganic substance; response to light stimulus; response to wounding; sensory perception of sound
Research Articles on Slc1a3
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Product Notes
The Rat Slc1a3 slc1a3 (Catalog #AAA9428062) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9428062 ELISA Kit recognizes Rat Slc1a3. It is sometimes possible for the material contained within the vial of "Excitatory amino acid transporter 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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