Monocarboxylate transporter 8 (SLC16A2) Recombinant Protein | SLC16A2 recombinant protein
Recombinant Human Monocarboxylate transporter 8 (SLC16A2), partial
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012]
Uniprot Description
Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. Does not transport Leu, Phe, Trp or Tyr.
Research Articles on SLC16A2
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Product Notes
The SLC16A2 slc16a2 (Catalog #AAA968546) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-539. The amino acid sequence is listed below: ALQSQASEEA KGPWQEADQE QQEPVGSPEP ESEPEPEPEP EPVPVPPPEP QPEPQPLPDP APLPELEFES ERVHEPEPTP TVETRGTARG FQPPEGGFGW VVVFAATWCN GSIFGIHNSV GILYSMLLEE EKEKNRQVEF QAAWVGALAM GMIFFCSPIV SIFTDRLGCR ITATAGAAVA FIGLHTSSFT SSLSLRYFTY GILFGCGCSF AFQPSLVILG HYFQRRLGLA NGVVSAGSSI FSMSFPFLIR MLGDKIKLAQ TFQVLSTFMF VLMLLSLTYR PLLPSSQDTP SKRGVRTLHQ RFLAQLRKYF NMRVFRQRTY RIWAFGIAAA ALGYFVPYVH LMKYVEEEFS EIKETWVLLV CIGATSGLGR LVSGHISDSI PGLKKIYLQV LSFLLLGLMS MMIPLCRDFG GLIVVCLFLG LCDGFFITIM APIAFELVGP MQASQAIGYL LGMMALPMIA GPPIAGLLRN CFGDYHVAFY FAGVPPIIGA VILFFVPLMH QRMFKKEQRD SSKDKMLAPD PDPNGELLPG SPNPEEPI. It is sometimes possible for the material contained within the vial of "Monocarboxylate transporter 8 (SLC16A2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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