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Typical Testing Data/Standard Curve (for reference only)

Human Apoptosis regulatory protein Siva ELISA Kit | SIVA1 elisa kit

Human Apoptosis regulatory protein Siva ELISA Kit

Gene Names
SIVA1; SIVA; CD27BP; Siva-1; Siva-2
Reactivity
Human
Synonyms
Apoptosis regulatory protein Siva; Human Apoptosis regulatory protein Siva ELISA Kit; CD27-binding protein; CD27BP; SIVA1; SIVA; SIVA1 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
175
Assay Type
Sandwich
Detection Range
78-5000 pg/mL
Sensitivity
35pg/mL
Intra-Assay CV
<=5.1%
Inter-Assay CV
<=10.5%
Recovery
106%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,778 Da
NCBI Official Full Name
apoptosis regulatory protein Siva isoform 1
NCBI Official Synonym Full Names
SIVA1 apoptosis inducing factor
NCBI Official Symbol
SIVA1
NCBI Official Synonym Symbols
SIVA; CD27BP; Siva-1; Siva-2
NCBI Protein Information
apoptosis regulatory protein Siva
UniProt Protein Name
Apoptosis regulatory protein Siva
UniProt Gene Name
SIVA1
UniProt Synonym Gene Names
SIVA; CD27BP
UniProt Entry Name
SIVA_HUMAN

NCBI Description

This gene encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

Siva: a proapoptotic protein. Associates with CD27, a member of the tumor necrosis factor receptor family. Two alternatively spliced isoforms have been described. Isoform 1 but not isoform 2 may induce TNFRSF7/CD27 mediated apoptosis. Isoform 1 inhibits Bcl-xL anti-apoptotic activity.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: cytoplasm; mitochondrion; nucleoplasm

Molecular Function: CD27 receptor binding; metal ion binding; protein binding; viral receptor activity; zinc ion binding

Biological Process: activated T cell apoptosis; entry of virus into host cell; inhibition of NF-kappaB transcription factor

Research Articles on SIVA1

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Product Notes

The Human SIVA1 siva1 (Catalog #AAA2883212) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883212 ELISA Kit recognizes Human SIVA1. It is sometimes possible for the material contained within the vial of "Apoptosis regulatory protein Siva, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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