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Kallikrein-13 Active Protein | KLK13 active protein

Recombinant Human Kallikrein-13, sf9

Gene Names
KLK13; KLKL4; KLK-L4
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Kallikrein-13; Recombinant Human Kallikrein-13; sf9; KLK13 Human; Kallikrein-13 Human Recombinant; Kallikrein-Related Peptidase 13; KLKL4; Kallikrein-Like Protein 4; Kallikrein 13; KLK-L4; Kallikrein-Like Gene 4; EC 3.4.21.-; EC 3.4.21; KLK13 active protein
Ordering
For Research Use Only!
Host
Sf9 Baculovirus Cells
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
KLK13 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Sterile Filtered colorless solution.
Sequence
GGVSQESSKV LNTNGTSGFL PGGYTCFPHS QPWQAALLVQ GRLLCGGVLVHPKWVLTAAH CLKEGLKVYL GKHALGRVEA GEQVREVVHS IPHPEYRRSP THLNHDHDIM LLELQSPVQLTGYIQTLPLS HNNRLTPGTT CRVSGWGTTT SPQVNYPKTL QCANIQLRSD EECRQVYPGKITDNMLCAGT KEGGKDSCEG DSGGPLVCNR TLYGIVSWGD FPCGQPDRPGVYTRVSRYVL WIRETIRKYE TQQQKWLKGP QHHHHHH
Sequence Length
277
Biological Activity
Specific activity is > 8,000 pmol/min/ug. One unit
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Related Product Information for KLK13 active protein
Introduction: Kallikreins are a subgroup of serine proteases having various physiological functions. Many kallikreins are implicated in carcinogenesis and some have potential of becoming novel cancer and other disease biomarkers. Kallikrein-13 (KLK13) is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK13 gene expression is regulated by steroid hormones and may be useful as a marker for breast cancer.

Description: KLK13 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 267 amino acids (17-277a.a.) and having a molecular mass of 29.7kDa. (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). KLK13 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Product Categories/Family for KLK13 active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13,986 Da
NCBI Official Full Name
kallikrein-13
NCBI Official Synonym Full Names
kallikrein related peptidase 13
NCBI Official Symbol
KLK13
NCBI Official Synonym Symbols
KLKL4; KLK-L4
NCBI Protein Information
kallikrein-13
UniProt Protein Name
Kallikrein-13
Protein Family
UniProt Gene Name
KLK13
UniProt Synonym Gene Names
KLKL4; KLK-L4
UniProt Entry Name
KLK13_HUMAN

Uniprot Description

KLK13: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]

Protein type: EC 3.4.21.-; Protease; Secreted; Secreted, signal peptide; Vesicle

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: cytoplasm; extracellular region; extracellular space

Molecular Function: hydrolase activity; protein binding; serine-type endopeptidase activity

Biological Process: protein processing

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Product Notes

The KLK13 klk13 (Catalog #AAA140736) is an Active Protein produced from Sf9 Baculovirus Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: GGVSQESSKV LNTNGTSGFL PGGYTCFPHS QPWQAALLVQ GRLLCGGVLV HPKWVLTAAH CLKEGLKVYL GKHALGRVEA GEQVREVVHS IPHPEYRRSP THLNHDHDIM LLELQSPVQL TGYIQTLPLS HNNRLTPGTT CRVSGWGTTT SPQVNYPKTL QCANIQLRSD EECRQVYPGK ITDNMLCAGT KEGGKDSCEG DSGGPLVCNR TLYGIVSWGD FPCGQPDRPG VYTRVSRYVL WIRETIRKYE TQQQKWLKGP QHHHHHH . It is sometimes possible for the material contained within the vial of "Kallikrein-13, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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