SERTAD2 recombinant protein
SERTAD2, 1-314aa, Human, His tag, E Coli
Gene Names
SERTAD2; Sei-2; TRIPBR2; TRIP-Br2
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
SERTAD2; 1-314aa; Human; His tag; E Coli; SERTA domain containing 2; Sei-2; TRIP-Br2; SERTAD2 recombinant protein
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Concentration
0.25 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMLGKGGK RKFDEHEDGL EGKIVSPCDG PSKVSYTLQR QTIFNISLMK LYNHRPLTEP SLQKTVLINN MLRRIQEELK QEGSLRPMFT PSSQPTTEPS DSYREAPPAF SHLASPSSHP CDLGSTTPLE ACLTPASLLE DDDDTFCTSQ AMQPTAPTKL SPPALLPEKD SFSSALDEIE ELCPTSTSTE AATAATDSVK GTSSEAGTQK LDGPQESRAD DSKLMDSLPG NFEITTSTGF LTDLTLDDIL FADIDTSMYD FDPCTSSSGT ASKMAPVSAD DLLKTLAPYS SQPVTPSQPF KMDLTELDHI MEVLVGS
Sequence Length
314
Applicable Applications for SERTAD2 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
Related Product Information for SERTAD2 recombinant protein
SERTA domain containing 2, also known as SERTAD2, acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Recombinant human SERTAD2 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for SERTAD2 recombinant protein
References
Cheong J.K., et al. (2009) J Transl Med. 7:8-8; Liew C.W., et al. (2013) Nat. Med. 19:217-226;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36.3 kDa (337aa) confirmed by MALDI-TOF
NCBI Official Full Name
SERTA domain-containing protein 2
NCBI Official Synonym Full Names
SERTA domain containing 2
NCBI Official Symbol
SERTAD2
NCBI Official Synonym Symbols
Sei-2; TRIPBR2; TRIP-Br2
NCBI Protein Information
SERTA domain-containing protein 2
UniProt Protein Name
SERTA domain-containing protein 2
Protein Family
UniProt Gene Name
SERTAD2
UniProt Synonym Gene Names
KIAA0127; TRIP-Br2
Uniprot Description
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F-target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism.
