Serpin I2 Recombinant Protein | SERPINI2 recombinant protein

Recombinant Human Serpin I2 Protein (C-6His)

Cat. Num. AAA2553224

• Gene Names: SERPINI2; MEPI; PI14; PANCPIN; TSA2004
• Purity: >95% as determined by reducing SDS-PAGE.
• Synonyms: Serpin I2; Recombinant Human Serpin I2 Protein (C-6His); SERPINI2; Myoepithelium-derived serine protease inhibitor; Pancreas-specific protein TSA2004; Peptidase inhibitor 14; PI-14; MEPI; PI14; SERPINI2 recombinant protein

• Host: Human Cells
• Purity/Purification: >95% as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
• Sequence Positions: Ser19-Leu405
• Sequence Length: 415

• Species: Human
• Endotoxin: <1.0 EU per ug as determined by LAL test.
• Fusion Tag: C-6His
• Preparation and Storage: Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.; Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.

Related Product Information for SERPINI2 recombinant protein

SERPINI2 is a secreted protein of the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. As protease inhibitors, serpins have an array of functions including regulating blood coagulation, fibrinolysis, the complement pathway, angiogenesis, inflammation, tumor suppression, extracellular matrix remodeling, and cell motility. SERPINI2 is expressed in human tissues including pancreas and adipose tissues. Mutations of human SERPINI2 can directly result in conditions such as acinar cell apoptosis and malabsorption.

NCBI and Uniprot Product Information

• NCBI GI #: 59814581
• NCBI GeneID: 5276
• NCBI Accession #: NP_001012303.1
• NCBI GenBank Nucleotide #: NM_001012303.2
• UniProt Accession #: O75830
• Molecular Weight: Molecular Mass: 45.1 kDa; Actual Protein Molecular Mass: 44-60 kDa
• NCBI Official Full Name: serpin I2 isoform 1
• NCBI Official Synonym Full Names: serpin family I member 2
• NCBI Official Symbol: SERPINI2
• NCBI Official Synonym Symbols: MEPI; PI14; PANCPIN; TSA2004
• NCBI Protein Information: serpin I2
• UniProt Protein Name: Serpin I2
• Protein Family: Serpin
• UniProt Gene Name: SERPINI2
• UniProt Synonym Gene Names: MEPI; PI14; PI-14

NCBI Description

The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]