Sentrin-Specific Protease 8/SENP8 Recombinant Protein | SENP8 recombinant protein
Recombinant Human Sentrin-Specific Protease 8/SENP8 Protein (N-6His)
Gene Names
SENP8; DEN1; NEDP1; PRSC2
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Sentrin-Specific Protease 8/SENP8; Recombinant Human Sentrin-Specific Protease 8/SENP8 Protein (N-6His); Sentrin-Specific Protease 8; Deneddylase-1; NEDD8-Specific Protease 1; Protease Cysteine 2; Sentrin/SUMO-Specific Protease SENP8; SENP8; DEN1; NEDP1; PRSC2; SENP8 recombinant protein
Host
E Coli
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Sequence Positions
Met1-Lys212
Sequence Length
212
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
N-6His
Preparation and Storage
Store at < -20 degree C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Related Product Information for SENP8 recombinant protein
Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2, CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 26.2 kDa
Actual Protein Molecular Mass: 22 kDa
Actual Protein Molecular Mass: 22 kDa
NCBI Official Full Name
sentrin-specific protease 8
NCBI Official Synonym Full Names
SUMO peptidase family member, NEDD8 specific
NCBI Official Symbol
SENP8
NCBI Official Synonym Symbols
DEN1; NEDP1; PRSC2
NCBI Protein Information
sentrin-specific protease 8
UniProt Protein Name
Sentrin-specific protease 8
Protein Family
UniProt Gene Name
SENP8
UniProt Synonym Gene Names
DEN1; NEDP1; PRSC2
NCBI Description
This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
Uniprot Description
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.
Research Articles on SENP8
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Product Notes
The SENP8 senp8 (Catalog #AAA2553208) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Met1-Lys212. It is sometimes possible for the material contained within the vial of "Sentrin-Specific Protease 8/SENP8, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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