Human SUMO1/sentrin/SMT3 specific peptidase 2 ELISA Kit | SENP2 elisa kit
Human Sentrin-specific protease 2, SENP2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM, Apr 2004]
Uniprot Description
SENP2: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Belongs to the peptidase C48 family.
Protein type: EC 3.4.22.68; Protease
Chromosomal Location of Human Ortholog: 3q27.2
Cellular Component: nucleoplasm; PML body; nuclear membrane; nuclear pore; cytoplasmic vesicle
Molecular Function: protein domain specific binding; protein binding; SUMO-specific protease activity
Biological Process: protein desumoylation; Wnt receptor signaling pathway; mRNA transport; heart development; regulation of Wnt receptor signaling pathway; dorsal/ventral axis specification; proteolysis; post-translational protein modification; negative regulation of DNA damage response, signal transduction by p53 class mediator; regulation of DNA endoreduplication; protein transport; cellular protein metabolic process; protein sumoylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of protein amino acid phosphorylation; negative regulation of protein binding
Research Articles on SENP2
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Product Notes
The Human SENP2 senp2 (Catalog #AAA9331824) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331824 ELISA Kit recognizes Human SENP2. It is sometimes possible for the material contained within the vial of "SUMO1/sentrin/SMT3 specific peptidase 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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