Human Sec61 alpha 2 subunit (S. cerevisiae) ELISA Kit | SEC61A2 elisa kit
Human Protein transport protein Sec61 subunit alpha isoform 2, SEC61A2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. It may also be required for the assembly of membrane and secretory proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Uniprot Description
SEC61A2: Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. Belongs to the SecY/SEC61-alpha family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Endoplasmic reticulum; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 10p14
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: ribosome binding
Biological Process: antigen processing and presentation of peptide antigen via MHC class I; protein transport; antigen processing and presentation of exogenous peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
Research Articles on SEC61A2
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Product Notes
The Human SEC61A2 sec61a2 (Catalog #AAA9327602) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9327602 ELISA Kit recognizes Human SEC61A2. It is sometimes possible for the material contained within the vial of "Sec61 alpha 2 subunit (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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