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118 results for "FLT3 inhibitor" - showing 1-50
Chemical Structure
Foretinib (GSK1363089, XL880), Inhibitor (Cat# AAA384812)
Full Name
Foretinib (GSK1363089, XL880)
Purity
>98%
Pricing
$125/5 mg | $200/25 mg | $300/50 mg | $465/100 mg | $150/1 mL (in DMSO) | $2,050/5x100 mg
Lestaurtinib (KT5555), Inhibitor (Cat# AAA515053)
Full Name
Lestaurtinib (KT5555)
Pricing
$185/5 mg | $290/25 mg | $1,080/5x25 mg
Structure
Dovitinib, Inhibitor (Cat# AAA579021)
Full Name
Dovitinib (TKI258) Lactate
Purity
98.0%
Pricing
$195/5 mg | $225/10 mg | $275/25 mg | $360/50 mg | $520/100 mg | $800/200 mg | $195/1 mL (in DMSO) | $3,340/5x200 mg
Structure
DCC-2036, Inhibitor (Cat# AAA577676)
Full Name
DCC-2036 (Rebastinib)
Purity
99.5%
Pricing
$190/2 mg | $210/5 mg | $240/10 mg | $315/25 mg | $360/50 mg | $215/1 mL (in DMSO) | $1,350/5x50 mg
Structure
Dovitinib, Inhibitor (Cat# AAA578847)
Full Name
Dovitinib
Purity
99.8%
Pricing
$195/2 mg | $210/5 mg | $225/10 mg | $295/25 mg | $370/50 mg | $545/100 mg | $855/200 mg | $225/1 mL (in DMSO) | $3,575/5x200 mg
Structure
Sorafenib tosylate, Inhibitor (Cat# AAA575466)
Full Name
Sorafenib tosylate
Purity
99.20%
Pricing
$165/1 mg | $175/5 mg | $185/10 mg | $195/50 mg | $205/100 mg | $215/500 mg | $210/200 mg | $205/1 mL (in DMSO) | $690/5x500 mg
Testing Data
(Ponatinib (AP24534) is a novel potent, orally available small molecule multitargeted kinase inhibitor with IC50 of 0.37, 2, 1.5, 2.2, 1.1, 1and 0.24 nM for native pan-BCR-ABL, mutated form, VEGFR2, FGFR1, PDGFRalpha, mutant FLT3 phosphorylation and LYN. It potently inhibited other clinically important ABL kinase domain mutants with IC50 from 0.30 to 0.44 nM and inhibited SRC with an IC50 of 5.4 nM. It inhibits the proliferation of mutant FLT3-positive cells with an IC50 of 13 nM and that inhibits mutant FLT3 phosphorylation with an IC50 of 1 nM and the proliferation of BCR-ABL1 T315I-positive Ba/F3 cells with an IC50 of 8 nM. It inhibited all tested BCR-ABL mutants with low nM IC50s in cellular and biochemical assays, suppressed BCR-ABL(T315I)-driven tumor growth in mice, and completely abrogated resistance in cell-based mutagenesis screens. AP24534 is used for treatment of CML. It did not inhibit Aurora kinase family members, nor did it inhibit insulin receptor or cyclin-dependent kinase 2 (CDK2)/Cyclin E (IC50 > 1000-fold relative to native ABL. [1][2][3])
Ponatinib, Inhibitor (Cat# AAA8506540)
Full Name
Ponatinib (AP24534)
Pricing
$440/10 mg | $1,940/5x10 mg
SB1317, Inhibitor (Cat# AAA5750089)
Full Name
SB1317 (TG-02) hydrochloride
Purity
98.1%
Pricing
$210/2 mg | $250/5 mg | $315/10 mg | $455/25 mg | $525/50 mg | $775/100 mg | $265/1 mL (in DMSO) | $3,230/5x100 mg
Structure
CYC116, Inhibitor (Cat# AAA579001)
Full Name
CYC116
Purity
98.0%
Pricing
$215/10 mg | $290/25 mg | $365/50 mg | $560/100 mg | $910/200 mg | $210/1 mL (in DMSO) | $3,815/5x200 mg
NCT-503, Inhibitor (Cat# AAA5750075)
Full Name
NCT-503
Purity
98.9%
Pricing
$205/5 mg | $240/10 mg | $335/25 mg | $480/50 mg | $665/100 mg | $945/200 mg | $205/1 mL (in DMSO) | $3,990/5x200 mg
SDS-Page
(Recombinant FLT3 (571-993) protein 10% SDS-PAGE with Coomassie staining MW: 49.7 kDa Purity: >50%)
FLT3, Recombinant Protein (Cat# AAA389425)
Full Name
Recombinant FLT3 (571-993) protein
Gene Names
FLT3; FLK2; STK1; CD135; FLK-2
Pricing
$545/0.02 mg | $4,100/1 mg | $18,390/5x1 mg
TAK-659, Inhibitor (Cat# AAA5750071)
Full Name
TAK-659 (hydrochloride)
Purity
99.3%
Pricing
$225/2 mg | $260/5 mg | $300/10 mg | $400/25 mg | $650/50 mg | $2,665/5x50 mg
FLT3-IN-1, Inhibitor (Cat# AAA577511)
Full Name
FLT3-IN-1
Purity
99.5%
Pricing
$265/2 mg | $305/5 mg | $400/10 mg | $590/25 mg | $870/50 mg | $1,220/100 mg | $330/1 mL (in DMSO) | $5,215/5x100 mg
Structure
Dovitinib, Inhibitor (Cat# AAA578758)
Full Name
Dovitinib (TKI-258) Dilactic Acid
Purity
98.0%
Pricing
$200/2 mg | $225/5 mg | $250/10 mg | $360/25 mg | $520/50 mg | $750/100 mg | $300/1mL*10mM (in DMSO) | $3,090/5x100 mg
Chemical Structure
Gilteritinib, Inhibitor (Cat# AAA5750530)
Full Name
Gilteritinib
Purity
97.8%
Pricing
$210/1 mg | $220/2 mg | $235/5 mg | $270/10 mg | $340/25 mg | $430/50 mg | $605/100 mg | $245/1 mL (in DMSO) | $2,445/5x100 mg
Structure
TCS 359, Inhibitor (Cat# AAA578706)
Full Name
TCS 359
Purity
99.02%
Pricing
$170/2 mg | $190/5 mg | $205/10 mg | $240/25 mg | $290/50 mg | $330/100 mg | $1,215/5x100 mg
Structure
Pacritinib, Inhibitor (Cat# AAA578596)
Full Name
Pacritinib (SB1518)
Purity
99.3%
Pricing
$195/2 mg | $210/5 mg | $240/10 mg | $305/25 mg | $375/50 mg | $210/1 mL (in DMSO) | $1,415/5x50 mg
Structure
AST 487, Inhibitor (Cat# AAA579957)
Full Name
AST 487
Purity
99.6%
Pricing
$210/1 mg | $255/2 mg | $340/5 mg | $505/10 mg | $800/25 mg | $990/50 mg | $435/1 mL (in DMSO) | $4,190/5x50 mg
Chemical Structure
(Chemical structure of Lestaurtinib (SIH-460), a FLT3/ TrkA kinase inhibitor. CAS #: 111358-88-4. Molecular Formula: C26H21N3O4. Molecular Weight: 439.5 g/mol.)
Lestaurtinib, Small Molecule (Cat# AAA808160)
Full Name
Lestaurtinib
Purity
>=98% (HPLC)
Pricing
$280/1 mg | $630/5 mg | $1,015/5x1 mg | $2,600/5x5 mg
Chemical Structure
CCT241736, Inhibitor (Cat# AAA5750545)
Full Name
CCT241736
Purity
98.0%
Pricing
$210/5 mg | $240/10 mg | $325/25 mg | $500/50 mg | $705/100 mg | $2,910/5x100 mg
Structure
AZ7550 Mesylate, Inhibitor (Cat# AAA5754248)
Full Name
AZ7550 Mesylate
Purity
98.00%
Pricing
$370/5 mg | $505/10 mg | $1,985/5x10 mg
Chemical Structure
UNC2025 2HCl, Inhibitor (Cat# AAA5750538)
Full Name
UNC2025 2HCl (1429881-91-3(Free Base))
Purity
98.6%
Pricing
$200/1 mg | $220/2 mg | $240/5 mg | $305/10 mg | $455/25 mg | $705/50 mg | $305/1 mL (in DMSO) | $2,905/5x50 mg
Chemical Structure
FLT3-IN-1, Inhibitor (Cat# AAA131238)
Full Name
FLT3-IN-1
Purity
98%
Pricing
$1,055/100 mg | $2,765/500 mg
Structure
UNC-2025, Inhibitor (Cat# AAA3607288)
Full Name
UNC-2025
Purity
>98% (HPLC)
Pricing
$190/2 mg | $205/5 mg | $245/10 mg | $355/25 mg | $555/50 mg | $2,190/5x50 mg
Chemical Structure
FLT3-IN-2, Inhibitor (Cat# AAA131191)
Full Name
FLT3-IN-2
Purity
98%
Pricing
$1,055/100 mg | $2,765/500 mg
Structure
Pexidartinib, Inhibitor (Cat# AAA3600138)
Full Name
Pexidartinib
Purity
>98% (HPLC)
Pricing
$190/5 mg | $205/10 mg | $260/50 mg | $285/100 mg | $330/200 mg | $1,185/5x200 mg
Structure
Dovitinib, Inhibitor (Cat# AAA3604393)
Full Name
Dovitinib
Purity
>98% (HPLC)
Pricing
$190/2 mg | $205/5 mg | $215/10 mg | $280/25 mg | $355/50 mg | $500/100 mg | $785/200 mg | $3,225/5x200 mg
Structure
AZ7550 hydrochloride, Inhibitor (Cat# AAA5754247)
Full Name
AZ7550 hydrochloride
Purity
98.00%
Pricing
$370/5 mg | $505/10 mg | $1,985/5x10 mg
Structure
CHIR-124, Inhibitor (Cat# AAA3604392)
Full Name
CHIR-124
Purity
>98% (HPLC)
Pricing
$190/2 mg | $225/5 mg | $265/10 mg | $360/25 mg | $555/50 mg | $760/100 mg | $3,145/5x100 mg
Structure
LDK378, Inhibitor (Cat# AAA3600160)
Full Name
LDK378
Purity
>98% (HPLC)
Pricing
$185/5 mg | $200/10 mg | $210/50 mg | $240/100 mg | $295/200 mg | $1,020/5x200 mg
Structure
KW-2449, Inhibitor (Cat# AAA3600007)
Full Name
KW-2449
Purity
>98% (HPLC)
Pricing
$215/10 mg | $370/50 mg | $1,380/5x50 mg
Structure
Merestinib dihydrochloride, Inhibitor (Cat# AAA5755136)
Full Name
Merestinib dihydrochloride
Purity
98.00%
Pricing
$240/2 mg | $280/5 mg | $355/10 mg | $705/50 mg | $1,065/100 mg | $330/1mL*10mM (in DMSO) | $4,505/5x100 mg
Structure
Trovirdine, Inhibitor (Cat# AAA3607318)
Full Name
Trovirdine
Purity
>98% (HPLC)
Pricing
$355/2 mg | $430/5 mg | $540/10 mg | $2,140/5x10 mg
Structure
UNC2025 2HCl (1429881-91-3 (free base)), Inhibitor (Cat# AAA3607702)
Full Name
UNC2025 2HCl (1429881-91-3 (free base))
Purity
>98% (HPLC)
Pricing
$230/5 mg | $280/10 mg | $390/25 mg | $595/50 mg | $2,390/5x50 mg
Structure
CGS 27023A, Inhibitor (Cat# AAA3607335)
Full Name
CGS 27023A
Purity
>98% (HPLC)
Pricing
$205/2 mg | $225/5 mg | $245/10 mg | $375/25 mg | $490/50 mg | $660/100 mg | $2,680/5x100 mg
ATH 686, Inhibitor (Cat# AAA3610978)
Full Name
ATH 686
Purity
>98% (HPLC)
Pricing
$390/5 mg | $520/10 mg | $835/25 mg | $3,465/5x25 mg
Structure
5'-Fluoroindirubinoxime, Inhibitor (Cat# AAA5759124)
Full Name
5'-Fluoroindirubinoxime
Purity
100.00%
Pricing
$295/5 mg | $475/25 mg | $295/1 mL (in DMSO) | $1,860/5x25 mg
Cabozantinib hydrochloride, Inhibitor (Cat# AAA5751609)
Full Name
Cabozantinib hydrochloride (849217-68-1 (free base))
Purity
98.00%
Pricing
$195/2 mg | $210/5 mg | $240/10 mg | $300/25 mg | $375/50 mg | $480/100 mg | $705/200 mg | $2,905/5x200 mg
Structure
5Z-7-Oxozeaenol, Inhibitor (Cat# AAA5754443)
Full Name
5Z-7-Oxozeaenol
Purity
98.00%
Pricing
$265/1 mg | $600/5 mg | $2,415/5x5 mg
Structure
TAK-659 hydrochloride, Inhibitor (Cat# AAA3603056)
Full Name
TAK-659 hydrochloride
Purity
>98% (HPLC)
Pricing
$215/2 mg | $250/5 mg | $285/10 mg | $375/25 mg | $600/50 mg | $2,410/5x50 mg
Structure
TAK-779, Inhibitor (Cat# AAA5758394)
Full Name
TAK-779
Purity
98.00%
Pricing
$215/2 mg | $240/5 mg | $305/10 mg | $430/25 mg | $585/50 mg | $310/1 mL (in DMSO) | $2,355/5x50 mg
TAK-659, Inhibitor (Cat# AAA3844895)
Full Name
TAK-659
Purity
>98%
Pricing
$210/5 mg | $300/10 mg | $795/50 mg | $1,535/100 mg | $6,855/5x100 mg
Structure
Structure
SB1317 hydrochloride (937270-47-8 (free base)), Inhibitor (Cat# AAA3607695)
Full Name
SB1317 hydrochloride (937270-47-8 (free base))
Purity
>98% (HPLC)
Pricing
$235/5 mg | $290/10 mg | $390/25 mg | $450/50 mg | $655/100 mg | $2,665/5x100 mg
Chemical Structure
Gilteritinib, Inhibitor (Cat# AAA3840353)
Full Name
Gilteritinib (ASP2215)
Purity
>98%
Pricing
$180/5 mg | $230/10 mg | $420/25 mg | $1,840/5x25 mg
Chemical Structure
AC710 Mesylate, Inhibitor (Cat# AAA3841514)
Full Name
AC710 Mesylate
Purity
>98%
Pricing
$200/5 mg | $285/10 mg | $930/50 mg | $4,130/5x50 mg
Chemical Structure
MRX-2843, Inhibitor (Cat# AAA3841933)
Full Name
MRX-2843
Purity
>98%
Pricing
$200/1 mg | $465/5 mg | $765/10 mg | $2,130/50 mg | $9,530/5x50 mg
Structure
BPR1J-097 hydrochloride (1327167-19-0 (free base)), Inhibitor (Cat# AAA3607697)
Full Name
BPR1J-097 hydrochloride (1327167-19-0 (free base))
Purity
>98% (HPLC)
Pricing
$225/5 mg | $265/10 mg | $505/50 mg | $705/100 mg | $2,880/5x100 mg
Structure
BMS-2, Inhibitor (Cat# AAA5759133)
Full Name
BMS-2
Purity
99.70%
Pricing
$240/1 mg | $330/5 mg | $445/10 mg | $730/25 mg | $3,020/5x25 mg
Structure
BPR1J-097, Inhibitor (Cat# AAA3607240)
Full Name
BPR1J-097
Purity
>98% (HPLC)
Pricing
$190/2 mg | $205/5 mg | $240/10 mg | $340/25 mg | $480/50 mg | $635/100 mg | $2,575/5x100 mg
