Secretin, alpha Recombinant Protein | Sct recombinant protein
Secretin, alpha, Recombinant, Human (GST)
Gene Names
Sct; Secr
Purity
Highly Purified90% as determined by both:
Synonyms
Secretin; alpha; Recombinant; Human (GST); Sct recombinant protein
Host
E Coli
Purity/Purification
Highly Purified
90% as determined by both:
90% as determined by both:
Form/Format
Supplied as a liquid in 50mM Tris buffer, pH 8.0 and 10mM glutathione.
Application Notes
Substrate for cell-free ubiquitination assays.
Preparation and Storage
-20 degree C
Stability: rGST-alpha Spectrin although stable at 140C for 1 week, should be stored desiccated below -180C. Please prevent freeze-thaw cycles.
Stability: rGST-alpha Spectrin although stable at 140C for 1 week, should be stored desiccated below -180C. Please prevent freeze-thaw cycles.
Related Product Information for Sct recombinant protein
Erythrocyte spectrin is the main component of the red cell membrane skeleton responsible for the shape and physical properties of red cells. Spectrin is composed of 2 subunits alpha and beta (280 and 246kD respectively). The human erithroid a-spectrin (2418 amino acids) consists of 22 repeating segments of about 106 amino acids in length. This protein was demonstrated to be a specific substrate for ubiquitina tion in vitro and in vivo. The main ubiquitination site on human a-spectrin was identified in the lysine 27 of the repeating segment 17 by sitedirected mutagenesis. Cell-free experiments using radiolabeled, biotinylated or native ubiquitin and cellular lysates from rabbit retyculocytes, human erythrocytes or k562 cells, showed that only monoubiquitination occurs at this site.
Recombinant fusion protein: Glutathione-S-Transferase (GST) and a fragment of human a-spectrin (from Lysine 1601 to Leucine 1818) containing repeat 17 and the ubiquitination target lysine 27. The total molecular weight of the fusion protein is 52.4kD.
Recombinant fusion protein: Glutathione-S-Transferase (GST) and a fragment of human a-spectrin (from Lysine 1601 to Leucine 1818) containing repeat 17 and the ubiquitination target lysine 27. The total molecular weight of the fusion protein is 52.4kD.
Product Categories/Family for Sct recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52.4kD
NCBI Official Full Name
secretin
NCBI Official Synonym Full Names
secretin
NCBI Official Symbol
Sct
NCBI Official Synonym Symbols
Secr
NCBI Protein Information
secretin
UniProt Protein Name
Secretin
Protein Family
UniProt Gene Name
Sct
UniProt Entry Name
SECR_RAT
NCBI Description
stimulates the secretion of bicarbonate-containing pancreatic fluid; may play a role in digestion [RGD, Feb 2006]
Uniprot Description
SCT: Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach. Belongs to the glucagon family.
Protein type: Secreted, signal peptide; Secreted
Cellular Component: extracellular space
Molecular Function: hormone activity; protein N-terminus binding; receptor binding
Biological Process: dentate gyrus development; positive regulation of cAMP biosynthetic process; visual learning; brain development; negative regulation of neuron apoptosis; embryonic gut development
Research Articles on Sct
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Product Notes
The Sct sct (Catalog #AAA637745) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. Substrate for cell-free ubiquitination assays. Researchers should empirically determine the suitability of the Sct sct for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Secretin, alpha, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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