Adenosylhomocysteinase Recombinant Protein | SAH1 recombinant protein

Recombinant Baker's yeast Adenosylhomocysteinase

Cat. Num. AAA1265181

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Adenosylhomocysteinase; Recombinant Baker's yeast Adenosylhomocysteinase; S-adenosyl-L-homocysteine hydrolase; SAH1 recombinant protein

• Host: E Coli
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Liquid containing glycerol
• Sequence Positions: 1-448aa; Full Length
• Sequence: MSAPAQNYKIADISLAAFGRKEIELAEHEMPGLMAIRKAYGDVQPLKGARIAGCLHMTIQTAVLIETLVALGAEVTWSSCNIYSTQDHAAAAIAASGVPVFAWKGETEEEYLWCIEQQLFAFKDNKKLNLILDDGGDLTTLVHEKHPEMLEDCFGLSEETTTGVHHLYRMVKEGKLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDVGKGCAAALRGMGARVLVTEIDPINALQAAMEGYQVVTMEDASHIGQVFVTTTGCRDIINGEHFINMPEDAIVCNIGHFDIEIDVAWLKANAKECINIKPQVDRYLLSSGRHVILLANGRLVNLGCATGHSSFVMSCSFSNQVLAQIALFKSNDKSFREKHIEFQKTGPFEVGVHVLPKILDEAVAKFHLGNLGVRLTKLSKVQSEYLGIPEEGPFKADHYR
• Sequence Length: 449

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for SAH1 recombinant protein

Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

References

The nucleotide sequence of Saccharomyces cerevisiae chromosome V.Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X., Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y., Botstein D., Davis R.W.Nature 387:78-81(1997) ) Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J., Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.Genome Res. 17:536-543(2007) Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.J. Proteome Res. 6:1190-1197(2007) Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) A multidimensional chromatography technology for in-depth phosphoproteome analysis.Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.Mol. Cell. Proteomics 7:1389-1396(2008) Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.Science 325:1682-1686(2009) N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) Sites of ubiquitin attachment in Saccharomyces cerevisiae.Starita L.M., Lo R.S., Eng J.K., von Haller P.D., Fields S.Proteomics 12:236-240(2012)

NCBI and Uniprot Product Information

• NCBI GI #: 398364417
• NCBI GeneID: 856766
• NCBI Accession #: NP_010961.3
• NCBI GenBank Nucleotide #: NM_001178934.3
• UniProt Accession #: P39954; D3DLU3
• Molecular Weight: 53 kDa
• NCBI Official Full Name: adenosylhomocysteinase
• NCBI Official Symbol: SAH1
• NCBI Protein Information: adenosylhomocysteinase
• UniProt Protein Name: Adenosylhomocysteinase
• Protein Family: Adenosylhomocysteinase
• UniProt Gene Name: SAH1
• UniProt Synonym Gene Names: AdoHcyase
• UniProt Entry Name: SAHH_YEAST

Uniprot Description

Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.