SAA2/Serum Amyloid A2 Recombinant Protein | SAA2 recombinant protein
Recombinant Human SAA2/Serum Amyloid A2 Protein (N-His)
Gene Names
SAA2; SAA; SAA1
Purity
>90% as determined by reducing SDS-PAGE.
Synonyms
SAA2/Serum Amyloid A2; Recombinant Human SAA2/Serum Amyloid A2 Protein (N-His); SAA; SAA2; Serum Amyloid A2; SAA2 recombinant protein
Host
E Coli
Purity/Purification
>90% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mMPB, 150mMNaCl, pH7.4.
Sequence
Arg19-Tyr122
Sequence Length
83
Species
Human
Endotoxin
< 1.0 EU per mug as determined by the LAL method.
Fusion Tag
N-His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for SAA2 recombinant protein
Protein Construction: Recombinant Human Serum amyloid A-2 protein is produced by our E Coli expression system and the target gene encoding Arg19-Tyr122 is expressed with a 6His tag at the N-terminus.
Background: Serum amyloid A-2 protein (SAA2) belongs to the SAA family. It expressed by the liver and secreted in plasma. SAA2 functions as major acute phase reactant and could works as apolipoprotein of the HDL complex. Increased levels of A-SAA in serum are indicative of inflammatory disease. When highly expressed, SAA can displace ApoA1 as the major apolipoprotein in HDL complexes, weakening the function of HDL as a reverse (lipid clearing) cholesterol transporter. A highly charged region of SAA2 and SAA1 (aa 36-68) contains putative fibronectin- and laminin-binding motifs. This region also binds heparin sulfate proteoglycans at mildly acidic pH and promotes aggregation of A-SAA.
Background: Serum amyloid A-2 protein (SAA2) belongs to the SAA family. It expressed by the liver and secreted in plasma. SAA2 functions as major acute phase reactant and could works as apolipoprotein of the HDL complex. Increased levels of A-SAA in serum are indicative of inflammatory disease. When highly expressed, SAA can displace ApoA1 as the major apolipoprotein in HDL complexes, weakening the function of HDL as a reverse (lipid clearing) cholesterol transporter. A highly charged region of SAA2 and SAA1 (aa 36-68) contains putative fibronectin- and laminin-binding motifs. This region also binds heparin sulfate proteoglycans at mildly acidic pH and promotes aggregation of A-SAA.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 13.2kDa
Actual Protein Molecular Mass: 14kDa
Actual Protein Molecular Mass: 14kDa
NCBI Official Full Name
serum amyloid A-2 protein isoform b
NCBI Official Synonym Full Names
serum amyloid A2
NCBI Official Symbol
SAA2
NCBI Official Synonym Symbols
SAA; SAA1
NCBI Protein Information
serum amyloid A-2 protein
UniProt Protein Name
Serum amyloid A-2 protein
Protein Family
UniProt Gene Name
SAA2
UniProt Synonym Gene Names
SAA2
Uniprot Description
Major acute phase reactant. Apolipoprotein of the HDL complex.
Research Articles on SAA2
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Product Notes
The SAA2 saa2 (Catalog #AAA2557141) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Arg19-Tyr1 22. It is sometimes possible for the material contained within the vial of "SAA2/Serum Amyloid A2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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