S100 Calcium Binding Protein P (S100P) Recombinant Protein | S100P recombinant protein

Recombinant S100 Calcium Binding Protein P (S100P)

Cat. Num. AAA2011248

• Gene Names: S100P; MIG9
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: S100 Calcium Binding Protein P (S100P); Recombinant S100 Calcium Binding Protein P (S100P); S100P recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with N-terminal His-Tag, its sequence is listed below.; MGHHHHHHSGS-MTELETAMGM IIDVFSRYSG SEGSTQTLTK GELKVLMEKE LPGFLQSGKD KDAVDKLLKD LDANGDAQVD FSEFIVFVAA ITSACHKYFE KAGLK
• Sequence Length: 95

• Applicable Applications for S100P recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Homo sapiens (Human)
• Expression System: Prokaryotic expression
• Residues: Met1~Lys95 (Accession # P25815) with N-terminal His-Tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

Sequence Information

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 5174663
• NCBI GeneID: 6286
• NCBI Accession #: NP_005971.1
• NCBI GenBank Nucleotide #: NM_005980.2
• UniProt Accession #: P25815; Q5J7W2
• Molecular Weight: 11.6kDa
• NCBI Official Full Name: protein S100-P
• NCBI Official Synonym Full Names: S100 calcium binding protein P
• NCBI Official Symbol: S100P
• NCBI Official Synonym Symbols: MIG9
• NCBI Protein Information: protein S100-P; protein S100-E; S100 calcium-binding protein P; migration-inducing gene 9 protein
• UniProt Protein Name: Protein S100-P
• Protein Family: Protein
• UniProt Gene Name: S100P
• UniProt Synonym Gene Names: S100E; MIG9
• UniProt Entry Name: S100P_HUMAN

NCBI Description

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008]

Uniprot Description

S100P: Homodimer. Interacts with S100PBP and S100Z. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. Belongs to the S-100 family.

Chromosomal Location of Human Ortholog: 4p16

Cellular Component: microvillus membrane; cytoplasm; nucleus

Molecular Function: protein binding; RAGE receptor binding; magnesium ion binding; calcium ion binding; calcium-dependent protein binding

Biological Process: response to organic substance; endothelial cell migration