S100A13 recombinant protein

S100A13, 1-98aa, Human, His tag, E Coli

Cat. Num. AAA203974

• Applications: SDS-Page
• Purity: > 95% by SDS-PAGE
• Synonyms: S100A13; 1-98aa; Human; His tag; E Coli; S100 calcium binding protein A13; S100A13 recombinant protein

• Host: E Coli
• Purity/Purification: > 95% by SDS-PAGE
• Form/Format: Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 50mM NaCl, 20% glycerol
• Concentration: 1 mg/ml (determined by BCA assay) (varies by lot)
• Sequence: MGSSHHHHHH SSGLVPRGSH MAAEPLTELE ESIETVVTTF FTFARQEGRK DSLSVNEFKE LVTQQLPHLL KDVGSLDEKM KSLDVNQDSE LKFNEYWRLI GELAKEIRKK KDLKIRKK
• Sequence Length: 98

• Applicable Applications for S100A13 recombinant protein: SDS-PAGE
• Antigen Species: Human
• Tag Information: His-tag
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for S100A13 recombinant protein

S100A13, also known as S100 calcium binding protein A13, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. S100A13 protein has been shown to interact with SYT1 and FGF1. Recombinant human S100A13 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography.

Product Categories/Family for S100A13 recombinant protein

Cell Cycle

References

Mandinova A., et al. (2003) Cell Sci. 116:2687-2696.; Jaurin B., et al. (1981) J Biol Chem. 281 (50):38905-17.

NCBI and Uniprot Product Information

• NCBI GI #: 66737374
• NCBI GeneID: 6284
• NCBI Accession #: NP_001019384
• NCBI GenBank Nucleotide #: NM_001024213.1
• UniProt Accession #: Q99584; Q52PI9; Q6FGF8
• Molecular Weight: 13.6 kDa (118aa), confirmed by MALDI-TOF
• NCBI Official Full Name: protein S100-A13
• NCBI Official Synonym Full Names: S100 calcium binding protein A13
• NCBI Official Symbol: S100A13
• NCBI Protein Information: protein S100-A13
• UniProt Protein Name: Protein S100-A13
• Protein Family: Protein
• UniProt Gene Name: S100A13

NCBI Description

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine ().