Human RUN and SH3 domain containing 1 ELISA Kit | RUSC1 elisa kit

Human RUN and SH3 domain-containing protein 1, RUSC1 ELISA Kit

Cat. Num. AAA9326708

• Gene Names: RUSC1; NESCA
• Reactivity: Human
• Synonyms: RUN and SH3 domain containing 1; Human RUN and SH3 domain-containing protein 1; RUSC1 ELISA Kit; Human RUN and SH3 domain-containing protein 1 (RUSC1) ELISA kit; RP11-21N7.4; DKFZp761A1822; NESCA; OTTHUMP00000015896; new molecule containing SH3 at the carboxy-terminus; RUSC1 elisa kit

• Reactivity: Human

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 157412245
• NCBI GeneID: 23623
• NCBI Accession #: NP_001098673.1
• NCBI GenBank Nucleotide #: NM_001105203.1
• UniProt Accession #: Q9BVN2; Q5T9U9; Q5T9V0; Q5T9V1; Q5T9V2; Q9UPY4; Q9Y4T5; B3KWM9
• Molecular Weight: 85,216 Da
• NCBI Official Full Name: RUN and SH3 domain-containing protein 1 isoform a
• NCBI Official Synonym Full Names: RUN and SH3 domain containing 1
• NCBI Official Symbol: RUSC1
• NCBI Official Synonym Symbols: NESCA
• NCBI Protein Information: RUN and SH3 domain-containing protein 1; new molecule containing SH3 at the carboxy-terminus
• UniProt Protein Name: RUN and SH3 domain-containing protein 1
• Protein Family: RUN and SH3 domain-containing protein
• UniProt Gene Name: RUSC1
• UniProt Synonym Gene Names: NESCA; Nesca
• UniProt Entry Name: RUSC1_HUMAN

Uniprot Description

RUSC1: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF- dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1q21-q22

Cellular Component: microtubule cytoskeleton; Golgi apparatus; postsynaptic membrane; microtubule; cytoplasmic membrane-bound vesicle; postsynaptic density; early endosome; cytoplasm; cytoplasmic vesicle; nucleus; cell junction

Molecular Function: protein binding; SH3/SH2 adaptor activity; actin binding

Biological Process: protein polyubiquitination; positive regulation of signal transduction