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Sphingoid long-chain base transporter RSB1 (RSB1) Recombinant Protein | RSB1 recombinant protein

Recombinant Saccharomyces cerevisiae Sphingoid long-chain base transporter RSB1 (RSB1)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Sphingoid long-chain base transporter RSB1 (RSB1); Recombinant Saccharomyces cerevisiae Sphingoid long-chain base transporter RSB1 (RSB1); Recombinant Sphingoid long-chain base transporter RSB1 (RSB1); Sphingoid long-chain base transporter RSB1; RSB1 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-382
Sequence
MSNATNNTLGSLLPQLEAAANSNSLYGGMVPNLRFNITMIVIWGILLTIHVVQLLMRQYWFSIAFICTGILEVLGFIGRTWSHSNVADMDAFLLNMICLTIAPVFTMGGIYYQLAKLIEVYGHRFSLLPSPMAYSFIFICSDIVSLVVQAVGGGLCGVAVTDGTSTTTGNHVFIAGLAIQVASMAIFLMLWFHFLFRIYISVRWEHINSRPISLSLLKISQTEVDYLYREKFHFLRLEPKRWVFHYFNLAMTVAVLTIFTRCCYRLAELVVGWDGYLITHEWYFIILDALMMAIATVTLTIFHPGFAFKGRSTSIPITPGHVDPETLPHTDDVEDILDTSDSKQFDIEKEEFQASMKYPISTFKQFMSKIANLFSSKKKAKL
Sequence Length
382
Species
Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

UniProt Accession #
Molecular Weight
43,205 Da
UniProt Protein Name
Sphingoid long-chain base transporter RSB1
UniProt Gene Name
RSB1
UniProt Entry Name
RSB1_YEAS1

Uniprot Description

Function: Catalyzes the ATP-dependent translocation of sphingoid long-chain bases (LCBs) from the cytoplasmic site toward the extracytoplasmic side of the membrane (flip-flop). Involved in the establishment of the functional lipid asymmetry of the plasma membrane. Regulates intracellular levels of LCBs, shingolipid precursors that are growth inhibitory at increased levels

By similarity.

Subcellular location: Cell membrane

By similarity; Multi-pass membrane protein.

Induction: In response to loss of mitochondrial DNA in a transcription factor PDR3-dependent manner. Induced in response to altered glycerophospholipid asymmetry of the plasma membrane in a transcription factor PDR1-dependent manner

By similarity.

Sequence similarities: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family. [View classification]

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Product Notes

The Sphingoid long-chain base transporter RSB1 (RSB1) rsb1 (Catalog #AAA1122189) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-382. The amino acid sequence is listed below: MSNATNNTLG SLLPQLEAAA NSNSLYGGMV PNLRFNITMI VIWGILLTIH VVQLLMRQYW FSIAFICTGI LEVLGFIGRT WSHSNVADMD AFLLNMICLT IAPVFTMGGI YYQLAKLIEV YGHRFSLLPS PMAYSFIFIC SDIVSLVVQA VGGGLCGVAV TDGTSTTTGN HVFIAGLAIQ VASMAIFLML WFHFLFRIYI SVRWEHINSR PISLSLLKIS QTEVDYLYRE KFHFLRLEPK RWVFHYFNLA MTVAVLTIFT RCCYRLAELV VGWDGYLITH EWYFIILDAL MMAIATVTLT IFHPGFAFKG RSTSIPITPG HVDPETLPHT DDVEDILDTS DSKQFDIEKE EFQASMKYPI STFKQFMSKI ANLFSSKKKA KL. It is sometimes possible for the material contained within the vial of "Sphingoid long-chain base transporter RSB1 (RSB1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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