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Human ring finger protein 125 ELISA Kit | RNF125 elisa kit

Human E3 ubiquitin-protein ligase RNF125, RNF125 ELISA Kit

Gene Names
RNF125; TRAC1; TRAC-1
Reactivity
Human
Synonyms
ring finger protein 125; Human E3 ubiquitin-protein ligase RNF125; RNF125 ELISA Kit; Human E3 ubiquitin-protein ligase RNF125 (RNF125) ELISA kit; FLJ20456; MGC21737; TRAC1; T-cell ring protein identified in activation screen; RNF125 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Preparation and Storage
Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,454 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase RNF125
NCBI Official Synonym Full Names
ring finger protein 125, E3 ubiquitin protein ligase
NCBI Official Symbol
RNF125
NCBI Official Synonym Symbols
TRAC1; TRAC-1
NCBI Protein Information
E3 ubiquitin-protein ligase RNF125; T-cell RING activation protein 1; T-cell ring protein identified in activation screen
UniProt Protein Name
E3 ubiquitin-protein ligase RNF125
UniProt Gene Name
RNF125
UniProt Synonym Gene Names
TRAC-1
UniProt Entry Name
RN125_HUMAN

NCBI Description

This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. [provided by RefSeq, Mar 2012]

Uniprot Description

RNF125: E3 ubiquitin-protein ligase that acts as a positive regulator of T-cell activation. E3 ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins.

Protein type: EC 6.3.2.-; Ubiquitin conjugating system; EC 6.3.2.19; Ligase; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 18q12.1

Molecular Function: zinc ion binding; ubiquitin-protein ligase activity; ligase activity

Biological Process: protein ubiquitination; innate immune response; negative regulation of interferon type I production

Disease: Tenorio Syndrome

Research Articles on RNF125

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Product Notes

The Human RNF125 rnf125 (Catalog #AAA9329482) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9329482 ELISA Kit recognizes Human RNF125. It is sometimes possible for the material contained within the vial of "ring finger protein 125, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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