Ribonuclease pancreatic (RNASE1) Recombinant Protein | RNASE1 recombinant protein

Recombinant Human Ribonuclease pancreatic (RNASE1) protein, C-His Tag

Cat. Num. AAA157488

• Gene Names: RNASE1; RAC1; RIB1; RNS1
• Purity: >90% as determined by SDS-PAGE
• Synonyms: Ribonuclease pancreatic (RNASE1); Recombinant Human Ribonuclease pancreatic (RNASE1) protein; C-His Tag; RIB1; RNS1; RNASE1 recombinant protein

• Host: E Coli
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized. Lyophilized from PBS pH 7.4, 0.2% NLS, 5% Trehalose, 5% Mannose, 1mM EDTA.

• Source: Human
• Reconstitution: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
• Construction: A DNA sequence encoding the human RNASE1 (Lys29-Thr156) was fused with the C-terminal His Tag
• Preparation and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for ~12 months from the date of receipt.; Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.; In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise

SDS-Page

Product Categories/Family for RNASE1 recombinant protein

Protein

NCBI and Uniprot Product Information

• NCBI GI #: 4506547
• NCBI GeneID: 6035
• NCBI Accession #: NP_002924.1
• NCBI GenBank Nucleotide #: NM_002933.5
• UniProt Accession #: P07998; Q16830; Q16869; Q1KHR2; Q6ICS5; Q9UCB4; Q9UCB5; B2R589; D3DS06
• Molecular Weight: 17,644 Da
• NCBI Official Full Name: ribonuclease pancreatic
• NCBI Official Synonym Full Names: ribonuclease A family member 1, pancreatic
• NCBI Official Symbol: RNASE1
• NCBI Official Synonym Symbols: RAC1; RIB1; RNS1
• NCBI Protein Information: ribonuclease pancreatic
• UniProt Protein Name: Ribonuclease pancreatic
• Protein Family: Ribonuclease pancreatic
• UniProt Gene Name: RNASE1
• UniProt Synonym Gene Names: RIB1; RNS1; RNase 1; RNase A

NCBI Description

This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA.