E3 ubiquitin-protein ligase RMA2 (RMA2) Recombinant Protein | RMA2 recombinant protein
Recombinant Arabidopsis thaliana E3 ubiquitin-protein ligase RMA2 (RMA2)
NCBI and Uniprot Product Information
NCBI Description
Encodes a RING finger E3 ubiquitin ligase. Binds and ubiquitinates ABP1 in vivo and in vitro.
Uniprot Description
Function: E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of the auxin-binding protein ERABP1. Ref.6 Ref.8
Pathway: Protein modification; protein ubiquitination.
Subunit structure: Interacts with ERABP1. Ref.8
Subcellular location: Endoplasmic reticulum membrane; Single-pass type IV membrane protein Ref.6.
Tissue specificity: Barely detected in roots and limited to the root tips. Expressed in leaf hydathodes and in siliques. Ref.1 Ref.6
Developmental stage: Expressed during seed development. Ref.1
Domain: The RING-type zinc finger domain is required for E3 ligase activity.
Disruption phenotype: No visible phenotype and no effect on drought stress response, probably due to the redundancy with RMA1 and RMA3. Ref.7
Sequence similarities: Contains 1 RING-type zinc finger.
Research Articles on RMA2
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Product Notes
The RMA2 rma2 (Catalog #AAA1189248) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-193. The amino acid sequence is listed below: MEIEKDEDDT TLVDSGGDFD CNICLDQVRD PVVTLCGHLF CWPCIHKWTY ASNNSRQRVD QYDHKREPPK CPVCKSDVSE ATLVPIYGRG QKAPQSGSNV PSRPTGPVYD LRGVGQRLGE GESQRYMYRM PDPVMGVVCE MVYRRLFGES SSNMAPYRDM NVRSRRRAMQ AEESLSRVYL FLLCFMFMCL FLF. It is sometimes possible for the material contained within the vial of "E3 ubiquitin-protein ligase RMA2 (RMA2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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