Human ras homolog gene family, member U ELISA Kit | RHOU elisa kit
Human Rho-related GTP-binding protein RhoU, RHOU ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011]
Uniprot Description
RHOU: Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP- bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. Belongs to the small GTPase superfamily. Rho family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein; G protein, monomeric, Rho; G protein, monomeric; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1q42.11-q42.3
Cellular Component: Golgi membrane; cell projection; focal adhesion; plasma membrane; podosome; cytosol
Molecular Function: GTPase activity; protein binding; GTP binding; metal ion binding
Biological Process: regulation of cell shape; regulation of small GTPase mediated signal transduction; metabolic process; small GTPase mediated signal transduction; Rac protein signal transduction; cytoskeleton organization and biogenesis; actin cytoskeleton organization and biogenesis; G1/S transition of mitotic cell cycle
Research Articles on RHOU
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Product Notes
The Human RHOU rhou (Catalog #AAA9339045) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9339045 ELISA Kit recognizes Human RHOU. It is sometimes possible for the material contained within the vial of "ras homolog gene family, member U, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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