Regulator Of G Protein Signaling 7 Recombinant Protein | RGS7 recombinant protein

Recombinant Regulator Of G Protein Signaling 7 (RGS7)

Cat. Num. AAA2034342

• Reactivity: Human
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >90%
• Synonyms: Regulator Of G Protein Signaling 7; Recombinant Regulator Of G Protein Signaling 7 (RGS7); RGS7 recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: >90%
• Sequence Length: 487

• Applicable Applications for RGS7 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Fragment: Met1~Glu144
• Tag: Prokaryotic expression
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 18314630
• NCBI GeneID: 6000
• Molecular Weight: 20.2kDa
• NCBI Official Full Name: Regulator of G-protein signaling 7
• NCBI Official Synonym Full Names: regulator of G-protein signaling 7
• NCBI Official Symbol: RGS7
• NCBI Protein Information: regulator of G-protein signaling 7
• UniProt Protein Name: Regulator of G-protein signaling 7
• Protein Family: Regulator of G-protein signaling
• UniProt Gene Name: RGS7
• UniProt Synonym Gene Names: RGS7
• UniProt Entry Name: RGS7_HUMAN

Uniprot Description

RGS7: inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations. Heterodimer with GNG5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with Gbeta5 (By similarity). Interacts with 14-3-3 protein Tau and SNAP25BP. Four alternatively spliced isoforms have been described.

Protein type: GAPs; GAPs, RGS

Chromosomal Location of Human Ortholog: 1q43|1q23.1

Cellular Component: cytoplasm; cytosol; heterotrimeric G-protein complex; nucleus; plasma membrane

Molecular Function: G-protein beta-subunit binding; GTPase activator activity; signal transducer activity

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of signal transduction; positive regulation of GTPase activity; regulation of G-protein coupled receptor protein signaling pathway