Regulator of G-protein signaling 4 (RGS4) Recombinant Protein | RGS4 recombinant protein
Recombinant Chicken Regulator of G-protein signaling 4 (RGS4)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Regulator of G-protein signaling 4 (RGS4); Recombinant Chicken Regulator of G-protein signaling 4 (RGS4); RGS4 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-208, Full length protein
Sequence
MCKGLAALPATCLKSAKDMKHRLGVLLQKSDSCDYGSSQGKKEKVSSSQRVSQEEVKKWAESLENLIHHDRGLAAFRAFLKSEYSEENIEFWVSCEDYKKTKSPAKLSTKARKIYDEFISVQATKEVNLDSCTREKTSHNMLEPTLSCFDEAQRKIFTLMEKDSYRRFLKSPYLDLVSPPRAGCGPENCKRAHAHALDCNSNIISQCA
Sequence Length
208
Species
Chicken
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for RGS4 recombinant protein
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,523 Da
NCBI Official Full Name
regulator of G-protein signaling 4
NCBI Official Synonym Full Names
regulator of G-protein signaling 4
NCBI Official Symbol
RGS4
NCBI Protein Information
regulator of G-protein signaling 4
UniProt Protein Name
Regulator of G-protein signaling 4
Protein Family
UniProt Gene Name
RGS4
UniProt Synonym Gene Names
RGS4
Uniprot Description
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein ().
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Product Notes
The RGS4 rgs4 (Catalog #AAA1307706) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-208, Full length protein. The amino acid sequence is listed below: MCKGLAALPA TCLKSAKDMK HRLGVLLQKS DSCDYGSSQG KKEKVSSSQR VSQEEVKKWA ESLENLIHHD RGLAAFRAFL KSEYSEENIE FWVSCEDYKK TKSPAKLSTK ARKIYDEFIS VQATKEVNLD SCTREKTSHN MLEPTLSCFD EAQRKIFTLM EKDSYRRFLK SPYLDLVSPP RAGCGPENCK RAHAHALDCN SNIISQCA. It is sometimes possible for the material contained within the vial of "Regulator of G-protein signaling 4 (RGS4), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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