RELM-beta Recombinant Protein | mRELM b recombinant protein

Recombinant Mouse RELM-beta

Gene Names

Retnlb; Xcp3; Fizz2; Relmb; RELMbeta; 9030012B21Rik

Purity

Greater than 97% as determined by SDS-PAGE.

Synonyms

RELM-beta; Recombinant Mouse RELM-beta; RELM b Mouse; RELM-Beta Mouse Recombinant; Resistin-like beta; RELM beta; Cysteine-rich secreted protein FIZZ2; Colon and small intestine-specific cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 1; Colon carcinoma-related gene protein; RELM-b; XCP2; HXCP2; mRELM b recombinant protein

Ordering
Cat. Num. AAA144100 For Research Use Only!

Host

E Coli

Purity/Purification

Greater than 97% as determined by SDS-PAGE.

Form/Format

The protein was lyophilized from a concentrated (1mg/ml) protein solution containing 10mM Acetic Acid with 2:1 mannitol to protein.
Brownish lyophilized powder.

Sequence

MQCSFESLVD QRIKEALSRQ EPKTISCTSV TSSGRLASCP AGMVVTGCAC GYGCGSWDIR NGNTCHCQCS VMDWASARCC RMA

Sequence Length

105

Solubility

Reconstitute at 0.1 mg/ml with sterile pyrogen free water.

Preparation and Storage

Lyophilized RETNLB is stable at -20 degree C. After reconstitution the protein should be kept at all times at -20 degree C. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.

Related Product Information for mRELM b recombinant protein

Description: Mouse RELM-b Recombinant produced in E Coli is a monomeric, non-glycosylated, polypeptide chain containing 83 amino acids and having a molecular mass of 8.9kDa. The Mouse RETNLB is purified by proprietary chromatographic techniques.

Introduction: RELM-beta (Resistin-Like Molecule-beta) is a member of a recently identified family of secreted proteins containing a conserved cystein-rich C-terminus. The RELM family consists of resistin (also called FIZZ3), RELM-alfa (FIZZ1), RELM-beta (FIZZ2) and RELM-gamma. Only resisistin and RELM-beta were found in humans whereas all four RELM family members were identified in rodents.RELM-beta appears to be produced as a homodimer exclusively by intestinal goblet cells and can be found in high quantities in stool. Remarkably, stool of germ-free mice displaying sterile intestinal tract does not contain RELM-beta until bacterial colonization takes place after pathogen-free mice entered natural environment. Some, but not all, colon carcinoma cell lines secrete RELM-beta into the cell culture supernatant.The physiological function of RELM-beta is not known. High doses of recombinant RELM-beta showed hyperglycemic effects including lowered glucose disposal and increased hepatic glucose production in mice.

Product Categories/Family for mRELM b recombinant protein

Cytokines and Growth Factors; Cytokines; Resistin

NCBI and Uniprot Product Information

NCBI GI #

225543345

NCBI GeneID

57263

NCBI Accession #

NP_076370.3

NCBI GenBank Nucleotide #

NM_023881.4

UniProt Accession #

Q99P86; Q9D286

Molecular Weight

11,278 Da

NCBI Official Full Name

resistin-like beta

NCBI Official Synonym Full Names

resistin like beta

NCBI Official Symbol

Retnlb

NCBI Official Synonym Symbols

Xcp3; Fizz2; Relmb; RELMbeta; 9030012B21Rik

NCBI Protein Information

resistin-like beta; cysteine-rich secreted protein A12-beta; cysteine-rich secreted protein FIZZ2; found in inflammatory zone 2; resistin-like molecule beta

UniProt Protein Name

Resistin-like beta

UniProt Gene Name

Retnlb

UniProt Synonym Gene Names

Fizz2

UniProt Entry Name

RETNB_MOUSE

Uniprot Description

resistin-like beta: Probable hormone. Belongs to the resistin/FIZZ family.

Cellular Component: extracellular region

Molecular Function: hormone activity

Research Articles on mRELM b

1. RELMbeta is abundantly expressed in foam cells within plaques and contributes to atherosclerosis development via lipid accumulation and inflammatory facilitation.

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Product Notes

The mRELM b retnlb (Catalog #AAA144100) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MQCSFESLVD QRIKEALSRQ EPKTISCTSV TSSGRLASCP AGMVVTGCAC GYGCGSWDIR NGNTCHCQCS VMDWASARCC RMA. It is sometimes possible for the material contained within the vial of "RELM-beta, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.