N-acylglucosamine 2-epimerase (RENBP) Recombinant Protein | RENBP recombinant protein

Recombinant Dog N-acylglucosamine 2-epimerase (RENBP)

Cat. Num. AAA1203508

• Gene Names: RENBP; AGE; RnBP
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: N-acylglucosamine 2-epimerase (RENBP); Recombinant Dog N-acylglucosamine 2-epimerase (RENBP); RENBP recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-35, Full length protein
• Sequence: LNLVDQLGEADEELAGTYAELGDWCAQRILQHVQR
• Sequence Length: 35

• Species: Canis familiaris (Dog) (Canis lupus familiaris)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for RENBP recombinant protein

The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature.

NCBI and Uniprot Product Information

• NCBI GI #: 55583788
• NCBI GeneID: 612532
• UniProt Accession #: O18921
• Molecular Weight: 3,955 Da
• NCBI Official Full Name: N-acylglucosamine 2-epimerase
• NCBI Official Symbol: RENBP
• NCBI Official Synonym Symbols: AGE; RnBP
• NCBI Protein Information: N-acylglucosamine 2-epimerase
• UniProt Protein Name: N-acylglucosamine 2-epimerase
• Protein Family: N-acylglucosamine 2-epimerase
• UniProt Gene Name: RENBP
• UniProt Synonym Gene Names: AGE; RnBP

Uniprot Description

Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits renin activity. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway ().