SDS-Page
Regenerating Islet Derived Protein 3 Gamma (REG3g) Recombinant Protein | REG3g recombinant protein
Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g)
MGHHHHHHSG SEF-VPTSRISC PKGSRAYGSY CYALFSVSKS WFDADLACQK RPSGHLVSVL SGSEASFVSS LIKSSGNSGQ NVWIGLHDPT LGQEPNRGGW EWSNADVMNY FNWETNPSSV SGSHCGT
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
SDS-Page
SDS-Page
NCBI and Uniprot Product Information
Uniprot Description
Function: Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury
By similarity.
Subcellular location: Secreted. Cytoplasm Ref.3.
Tissue specificity: Expressed in injured skeletal muscles and sciatic nerve (at protein level). Expressed in the pancreas. Expression increases during the acute phase of pancreatitis. Ref.2 Ref.3
Induction: Up-regulated in injured skeletal muscles and peripheral nerve. Ref.3
Domain: The EPN motif is essential for recognition of the peptidoglycan carbohydrate backbone and for efficient bacterial killing with Glu-114 playing a key role in peptidoglycan binding and bactericidal activity
By similarity.
Post-translational modification: Proteolytic processing by trypsin removes an inhibitory N-terminal propeptide and is essential for peptidoglycan binding and antibacterial activity
By similarity.
Sequence similarities: Contains 1 C-type lectin domain.
Research Articles on REG3g
Similar Products
Product Notes
The REG3g reg3g (Catalog #AAA2010204) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Regenerating Islet Derived Protein 3 Gamma (REG3g) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the REG3g reg3g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSG SEF-VPTSRI SC PKGSRAYGSY CYALFSVSKS WFDADLACQK RPSGHLVSVL SGSEASFVSS LIKSSGNSGQ NVWIGLHDPT LGQEPNRGGW EWSNADVMNY FNWETNPSSV SGSHCGT. It is sometimes possible for the material contained within the vial of "Regenerating Islet Derived Protein 3 Gamma (REG3g), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
