Human Lithostathine-1-alpha ELISA Kit | REG1A elisa kit

Human Lithostathine-1-alpha ELISA Kit

Cat. Num. AAA2880054

• Gene Names: REG1A; P19; PSP; PTP; REG; ICRF; PSPS; PSPS1
• Reactivity: Human
• Synonyms: Lithostathine-1-alpha; Human Lithostathine-1-alpha ELISA Kit; Islet cells regeneration factor; ICRF; Islet of Langerhans regenerating protein; REG; Pancreatic stone protein; PSP; Pancreatic thread protein; PTP; REG1A elisa kit

• Reactivity: Human
• Specificity: Recombinant and natural Rat Lipoprotein lipase (LPL)
• Sequence Length: 166

• Samples: Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids
• Detection Range: 0.78 ng/mL-50 ng/mL
• Sensitivity: <0.419 ng/mL
• Intra-assay Precision: Intra-Assay CV: <3.8%
• Inter-assay Precision: Inter-Assay CV: <6.3%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for REG1A elisa kit

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 29725633
• NCBI GeneID: 5967
• NCBI Accession #: NP_002900.2
• NCBI GenBank Nucleotide #: NM_002909.4
• UniProt Accession #: P05451; P11379; Q4ZG28
• Molecular Weight: 18,731 Da
• NCBI Official Full Name: lithostathine-1-alpha
• NCBI Official Synonym Full Names: regenerating family member 1 alpha
• NCBI Official Symbol: REG1A
• NCBI Official Synonym Symbols: P19; PSP; PTP; REG; ICRF; PSPS; PSPS1
• NCBI Protein Information: lithostathine-1-alpha
• UniProt Protein Name: Lithostathine-1-alpha
• Protein Family: Lithostathine
• UniProt Gene Name: REG1A
• UniProt Synonym Gene Names: PSPS; PSPS1; REG; ICRF; REG; PSP; PTP; REG-1-alpha
• UniProt Entry Name: REG1A_HUMAN

NCBI Description

This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008]

Uniprot Description

REG1A: Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2p12

Molecular Function: carbohydrate binding; growth factor activity

Biological Process: positive regulation of cell proliferation