Western Blot (WB)
(Western Blot analysis of PRRX2 expression in transfected 293T cell line by PRRX2 polyclonal antibody. Lane 1: PRRX2 transfected lysate (27.83kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human PRRX2 Polyclonal Antibody | anti-PRRX2 antibody
PRRX2 (Paired Mesoderm Homeobox Protein 2, Paired-related Homeobox Protein 2, PMX2, PRX2, PRX-2)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of PRRX2 expression in transfected 293T cell line by PRRX2 polyclonal antibody. Lane 1: PRRX2 transfected lysate (27.83kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of PRRX2 expression in transfected 293T cell line by PRRX2 polyclonal antibody. Lane 1: PRRX2 transfected lysate (27.83kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008]
Uniprot Description
PRRX2: May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development. Belongs to the paired homeobox family.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 9q34.1
Cellular Component: nucleus
Molecular Function: sequence-specific DNA binding; transcription factor activity
Biological Process: inner ear morphogenesis; regulation of transcription, DNA-dependent; cartilage development; positive regulation of mesenchymal cell proliferation; artery morphogenesis; positive regulation of smoothened signaling pathway; embryonic cranial skeleton morphogenesis; middle ear morphogenesis; embryonic limb morphogenesis
Research Articles on PRRX2
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Product Notes
The PRRX2 prrx2 (Catalog #AAA6012048) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PRRX2 (Paired Mesoderm Homeobox Protein 2, Paired-related Homeobox Protein 2, PMX2, PRX2, PRX-2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PRRX2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the PRRX2 prrx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MDSAAAAFAL DKPALGPGPP PPPPALGPGD CAQARKNFSV SHLLDLEEVA AAGRLAARPG ARAEAREGAA REPSGGSSGS EAAPQDGECP SPGRGSAAKR KKKQRRNRTT FNSSQLQALE RVFERTHYPD AFVREELARR VNLSEARVQV WFQNRRAKFR RNERAMLASR SASLLKSYSQ EAAIEQPVAP RPTALSPDYL SWTASSPYST VPPYSPGSSG PATPGVNMAN SIASLRLKAK EFSLHHSQVP TVN. It is sometimes possible for the material contained within the vial of "PRRX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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