Protein Tyrosine Phosphatase, Non-receptor Type 1, catalytic domain, Active Protein | PTPN20B active protein

Protein Tyrosine Phosphatase, Non-receptor Type 1, catalytic domain, (1-321), Recombinant, Rat (PTPN (PTPN1, Protein Tyrosine Phosphatase 1B, Placental Protein Tyrosine Phosphatase)

Cat. Num. AAA637336

• Gene Names: PTPN20B; bA42B19.1
• Reactivity: Rat
• Purity: >95% by SDS-PAGE.
• Synonyms: Protein Tyrosine Phosphatase; Non-receptor Type 1; catalytic domain; ; (1-321); Recombinant; Rat (PTPN (PTPN1; Protein Tyrosine Phosphatase 1B; Placental Protein Tyrosine Phosphatase); PTPN20B active protein

• Host: Recombinant, rat from E Coli
• Reactivity: Rat
• Purity/Purification: >95% by SDS-PAGE.
• Form/Format: 25 mM Tris-HCl, pH 8.0, 75 mM sodium chloride, 0.05% Tween-20, 50% glycerol, 2mM EDTA, 3mM DTT.

• Application Notes: useful for the study of enzyme kinetics, regulation, to dephosphorylate target substrates and for screening inhibitors.
• Specific Activity: 20 U/ug. One unit will hydrolyze 1 nmol p-nitrophenyl phosphate per minute at pH 7.4 and 30 degree C
• Assay Buffer: 50 mM HEPES, pH 7.4, 2 mM EDTA, 3 mM DTT, 100 mM NaCl, 50mM pNPP.
• Preparation and Storage: -70 degree C; Stability: 6 months at -20 degree C

Related Product Information for PTPN20B active protein

Catalytic domain, (a.a. 1-321), MW=37.3kD, expressed in an E. coli expression system

Product Categories/Family for PTPN20B active protein

Molecular Biology; MB-Enzymes; Phosphatase

NCBI and Uniprot Product Information

• NCBI GI #: 108802604
• NCBI GeneID: 26095
• NCBI Accession #: NP_001035816.1
• NCBI GenBank Nucleotide #: NM_001042357.3
• NCBI Official Full Name: protein tyrosine phosphatase, non-receptor type 20 isoform 1
• NCBI Official Synonym Full Names: protein tyrosine phosphatase, non-receptor type 20B
• NCBI Official Symbol: PTPN20B
• NCBI Official Synonym Symbols: bA42B19.1
• NCBI Protein Information: protein tyrosine phosphatase, non-receptor type 20

NCBI Description

The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more telomeric copy, PTPN20B. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]