RNA Binding Motif Protein 3 Recombinant Protein | RBM3 recombinant protein

Recombinant Human RNA Binding Motif Protein 3

Cat. Num. AAA145900

• Gene Names: RBM3; RNPL; IS1-RNPL
• Purity: Greater than 95.0% as determined by SDS-PAGE.
• Synonyms: RNA Binding Motif Protein 3; Recombinant Human RNA Binding Motif Protein 3; RBM3 Human; RNA Binding Motif Protein 3 Human Recombinant; IS1-RNPL; RNPL; RNA-binding motif protein 3; Putative RNA-Binding Protein 3; RNA Binding Motif (RNP1; RRM) Protein 3; RBM3 recombinant protein

• Host: E Coli
• Purity/Purification: Greater than 95.0% as determined by SDS-PAGE.
• Form/Format: RBM3 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol and 5mM DTT.; Sterile Filtered clear solution.
• Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSSEEGK LFVGGLNFNT DEQALEDHFS SFGPISEVVV VKDRETQRSRGFGFITFTNP EHASVAMRAM NGESLDGRQI RVDHAGKSAR GTRGGGFGAH GRGRSYSRGG GDQGYGSGRYYDSRPGGYGY GYGRSRDYNG RNQGGYDRYS GGNYRDNYDN
• Sequence Length: 157

Related Product Information for RBM3 recombinant protein

Description: RBM3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 180 amino acids (1-157 a.a) and having a molecular mass of 19kDa. RBM3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: RBM3 belongs to the glycine-rich RNA-binding protein family and encodes a protein

Product Categories/Family for RBM3 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; RNA Binding Motif Protein

NCBI and Uniprot Product Information

• NCBI GI #: 5803137
• NCBI GeneID: 5935
• NCBI Accession #: NP_006734.1
• NCBI GenBank Nucleotide #: NM_006743.4
• UniProt Accession #: P98179
• Molecular Weight: 17,170 Da
• NCBI Official Full Name: RNA-binding protein 3
• NCBI Official Synonym Full Names: RNA binding motif (RNP1, RRM) protein 3
• NCBI Official Symbol: RBM3
• NCBI Official Synonym Symbols: RNPL; IS1-RNPL
• NCBI Protein Information: RNA-binding protein 3; RNA-binding motif protein 3; putative RNA-binding protein 3
• UniProt Protein Name: RNA-binding protein 3
• Protein Family: RNA-binding protein
• UniProt Gene Name: RBM3
• UniProt Synonym Gene Names: RNPL
• UniProt Entry Name: RBM3_HUMAN

NCBI Description

This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2008]

Uniprot Description

RBM3: Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation.

Protein type: Ribosomal; Translation; RNA-binding; RNA processing

Chromosomal Location of Human Ortholog: Xp11.2

Cellular Component: cytoplasm; dendrite; nucleus; large ribosomal subunit

Molecular Function: protein binding; RNA binding; nucleotide binding; ribosomal large subunit binding

Biological Process: RNA processing; regulation of translation; miRNA-mediated gene silencing, production of miRNAs; positive regulation of translation; translation; response to cold