Glycine-rich RNA-binding protein 8 (GRP8) Recombinant Protein | GRP8 recombinant protein
Recombinant Arabidopsis thaliana Glycine-rich RNA-binding protein 8 (GRP8)
NCBI and Uniprot Product Information
NCBI Description
Encodes a glycine-rich protein with RNA binding domain at the N-terminus. Protein is structurally similar to proteins induced by stress in other plants. Gene expression is induced by cold. Transcript undergoes circadian oscillations that is depressed by overexpression of AtGRP7. A substrate of the type III effector HopU1 (mono-ADP-ribosyltransferase).
Uniprot Description
Plays a role in RNA transcription or processing during stress. Binds RNAs and DNAs sequence with a preference to single-stranded nucleic acids. Involved in mRNA alternative splicing of numerous targets by modulating splice site selection. Negatively regulates the circadian oscillations of its own transcript as well as RBG7 transcript. Forms an interlocked post-transcriptional negative feedback loop with the RBG7 autoregulatory circuit. Both proteins negatively autoregulate and reciprocally crossregulate by binding to their pre-mRNAs and promoting unproductive splicing coupled to degradation via the NMD pathway. Target of the Pseudomonas syringae type III effector HopU1.
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Product Notes
The GRP8 rbg8 (Catalog #AAA1028594) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-169, Full length protein. The amino acid sequence is listed below: MSEVEYRCFV GGLAWATNDE DLQRTFSQFG DVIDSKIIND RESGRSRGFG FVTFKDEKAM RDAIEEMNGK ELDGRVITVN EAQSRGSGGG GGGRGGSGGG YRSGGGGGYS GGGGGGYSGG GGGGYERRSG GYGSGGGGGG RGYGGGGRRE GGGYGGGDGG SYGGGGGGW. It is sometimes possible for the material contained within the vial of "Glycine-rich RNA-binding protein 8 (GRP8), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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