Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) Standard Curve.)
Rat Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3) ELISA Kit | RIPK3 elisa kit
Rat Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) Standard Curve.)
Background: Receptor-interacting serine/threonine-protein kinase 3 is an enzyme that in humans is encoded by the RIPK3 gene. The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
NCBI and Uniprot Product Information
NCBI Description
a putative homocysteine respondent protein [RGD, Feb 2006]
Uniprot Description
RIPK3: Promotes apoptosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Binds TRAF2 and RIPK1 and is recruited to the TNFR-1 signaling complex. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, TKL; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; TKL group; RIPK family
Cellular Component: cytosol; intracellular; mitochondrion; plasma membrane
Molecular Function: ATP binding; identical protein binding; NF-kappaB-inducing kinase activity; protein complex binding; protein kinase activity; protein serine/threonine kinase activity
Biological Process: activation of NF-kappaB transcription factor; activation of protein kinase activity; I-kappaB kinase/NF-kappaB cascade; lymph node development; positive regulation of ligase activity; positive regulation of oxidoreductase activity; protein amino acid autophosphorylation; protein heterooligomerization; protein homooligomerization; regulation of activated T cell proliferation; regulation of adaptive immune response; regulation of interferon-gamma production; regulation of T cell mediated cytotoxicity; spleen development; T cell differentiation in the thymus; T cell homeostasis; thymus development
Research Articles on RIPK3
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Product Notes
The Rat RIPK3 ripk3 (Catalog #AAA9711919) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9711919 ELISA Kit recognizes Rat RIPK3. It is sometimes possible for the material contained within the vial of "Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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