Rat Protein Kinase, AMP Activated Beta 1 (PRKAb1) ELISA Kit | PRKAb1 elisa kit

Rat Protein Kinase, AMP Activated Beta 1 (PRKAb1) ELISA Kit

Cat. Num. AAA455137

• Reactivity: Rat
• Synonyms: Protein Kinase; AMP Activated Beta 1 (PRKAb1); Rat Protein Kinase; AMP Activated Beta 1 (PRKAb1) ELISA Kit; ABCB1; CD243; ABC20; CLCS; GP170; MDR1; P-Gp; PGY1; P-Glycoprotein;; PRKAb1 elisa kit

• Reactivity: Rat
• Sequence Length: 270

• Samples: Tissue homogenates, cell lysates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.156-10ng/mL
• Sensitivity: 0.060ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 14010877
• NCBI GeneID: 83803
• NCBI Accession #: NP_114182.1
• NCBI GenBank Nucleotide #: NM_031976.1
• UniProt Accession #: P80386; Q63048
• Molecular Weight: 30,394 Da
• NCBI Official Full Name: 5'-AMP-activated protein kinase subunit beta-1
• NCBI Official Synonym Full Names: protein kinase AMP-activated non-catalytic subunit beta 1
• NCBI Official Symbol: Prkab1
• NCBI Protein Information: 5'-AMP-activated protein kinase subunit beta-1
• UniProt Protein Name: 5'-AMP-activated protein kinase subunit beta-1
• Protein Family: 5'-AMP-activated protein kinase
• UniProt Gene Name: Prkab1
• UniProt Synonym Gene Names: AMPK subunit beta-1; AMPKb

NCBI Description

may facilitate the association of the heterotrimeric AMP-activated protein kinase; may phosphorylate and inactivate enzymes involved in lipid metabolism; may play a role in response to metabolic stress [RGD, Feb 2006]

Uniprot Description

Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).