Rat PRA1 family protein 3 (ARL6IP5) ELISA Kit | ARL6IP5 elisa kit
Rat PRA1 family protein 3 (ARL6IP5) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport. [provided by RefSeq, Jul 2008]
Uniprot Description
ARL6IP5: Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic. Belongs to the PRA1 family.
Protein type: Endoplasmic reticulum; Cytoskeletal; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 3p14
Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane
Molecular Function: protein C-terminus binding
Biological Process: L-glutamate transport; positive regulation of apoptosis; positive regulation of caspase activity; negative regulation of transport; induction of apoptosis by oxidative stress; positive regulation of stress-activated MAPK cascade
Research Articles on ARL6IP5
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Product Notes
The Rat ARL6IP5 arl6ip5 (Catalog #AAA7220928) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7220928 ELISA Kit recognizes Rat ARL6IP5. It is sometimes possible for the material contained within the vial of "PRA1 family protein 3 (ARL6IP5), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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