Rat MAS1 oncogene ELISA Kit | MAS1 elisa kit
Rat Proto-oncogene Mas, MAS1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
oncogene; may be involved in function or development of neural tissues [RGD, Feb 2006]
Uniprot Description
MAS1: Receptor for angiotensin 1-7. Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Oncoprotein
Cellular Component: cell surface; plasma membrane; integral to membrane
Molecular Function: G-protein coupled receptor activity; peptide hormone binding; peptide binding; angiotensin receptor activity
Biological Process: response to drug; G-protein coupled receptor protein signaling pathway; response to peptide hormone stimulus; negative regulation of protein amino acid phosphorylation; male gonad development; regulation of inflammatory response; positive regulation of cell proliferation; hippocampus development; activation of NF-kappaB-inducing kinase; spermatogenesis; response to activity; positive regulation of DNA replication