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Typical Testing Data/Standard Curve (for reference only)

Rat Fibrinogen Alpha Chain ELISA Kit | FGA elisa kit

Rat Fibrinogen Alpha Chain ELISA Kit

Reactivity
Rat
Synonyms
Fibrinogen Alpha Chain; Rat Fibrinogen Alpha Chain ELISA Kit; FGA elisa kit
Ordering
For Research Use Only!
Reactivity
Rat
Sequence Length
28
Samples
Serum, plasma, cell culture supernate and other biological fluids
Assay Type
Sandwich
Detection Range
1.25 mug/ml-20 mug/ml
Sensitivity
0.1 mug/ml

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for FGA elisa kit
Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofFIBRINOGEN ALPHA CHAINin the sample, This FIBRINOGEN ALPHA CHAINELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusFIBRINOGEN ALPHA CHAINconcentration. The concentration ofFIBRINOGEN ALPHA CHAINin the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Fibrinogen alpha chain
NCBI Official Synonym Full Names
fibrinogen alpha chain
NCBI Official Symbol
FGA
NCBI Protein Information
fibrinogen alpha chain
UniProt Protein Name
Fibrinogen alpha chain
Protein Family
UniProt Gene Name
FGA
UniProt Entry Name
FIBA_CANFA

Uniprot Description

Function: Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.

Subunit structure: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain

By similarity.

Subcellular location: Secreted.

Domain: A long coiled coil structure formed by 3 polypeptide chains connects the central nodule to the C-terminal domains (distal nodules). The long C-terminal ends of the alpha chains fold back, contributing a fourth strand to the coiled coil structure.

Post-translational modification: Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. The soft clot is converted into the hard clot by factor XIIIA which catalyzes the epsilon-(gamma-glutamyl)lysine cross-linking between gamma chains (stronger) and between alpha chains (weaker) of different monomers.Forms F13A-mediated cross-links between a glutamine and the epsilon-amino group of a lysine residue, forming fibronectin-fibrinogen heteropolymers.

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Product Notes

The Rat FGA fga (Catalog #AAA3809262) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA3809262 ELISA Kit recognizes Rat FGA. It is sometimes possible for the material contained within the vial of "Fibrinogen Alpha Chain, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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