Rat DYNLL1/Dynein Light Chain 1, Cytoplasmic ELISA Kit | DYNLL1 elisa kit
Rat DYNLL1/Dynein Light Chain 1, Cytoplasmic ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
inhibitor of neuronal nitric oxide synthase, a mediator of apoptosis, synaptogenesis, and neuronal development in the brain [RGD, Feb 2006]
Uniprot Description
LC8: a highly conserved cytoplasmic protein of the dynein light chain family. Cytoplasmic dyneins are large enzyme complexes. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain. Interacts with and inhibits the activity of neuronal nitric oxide synthase (nNOS). A highly conserved protein, showing 92% amino acid similarity with the nematode homolog. Binding of this protein destabilizes the nNOS dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity.
Protein type: Microtubule-binding; Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 12q16
Cellular Component: centrosome; cytoplasm; cytoplasmic dynein complex; cytoskeleton; cytosol; kinetochore; membrane; nucleus; signalosome
Molecular Function: dynein intermediate chain binding; enzyme binding; enzyme inhibitor activity; nitric-oxide synthase regulator activity; protein binding; protein C-terminus binding; protein domain specific binding; protein homodimerization activity
Biological Process: negative regulation of phosphorylation; neurotransmitter metabolic process; nitric oxide biosynthetic process; substantia nigra development
Research Articles on DYNLL1
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Product Notes
The Rat DYNLL1 dynll1 (Catalog #AAA2890164) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2890164 ELISA Kit recognizes Rat DYNLL1. It is sometimes possible for the material contained within the vial of "DYNLL1/Dynein Light Chain 1, Cytoplasmic, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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