Typical Testing Data/Standard Curve (for reference only)
Rat DNA Methyltransferase 3A (DNMT3A) ELISA Kit | DNMT3A elisa kit
Rat DNA Methyltransferase 3A (DNMT3A) ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
member of a family of DNA methyltransferases [RGD, Feb 2006]
Uniprot Description
DNMT3A: a DNA methyltransferase required for genome wide de novo methylation and essential for development. DNA methylation is coordinated with methylation of histones. Prefers CpG methylation to CpA, CpT, and CpC methylation. Methylates CpG sites at a rate much slower than DNMT1, but greater than DNMT3b. Methylation is coordinated with methylation of histones. Binds the ZNF238 transcriptional repressor. Interacts with SETDB1 and DNMT1. Can co-localize with heterochromatin protein (HP1 ) and methyl-CpG binding protein (MeCBP). Associates with HDAC1 through its ADD-type zinc-finger. Highly expressed in fetal tissues, skeletal muscle, heart, peripheral blood mononuclear cells, kidney, and at lower levels in placenta, brain, liver, colon, spleen, small intestine and lung.
Protein type: Amino Acid Metabolism - cysteine and methionine; EC 2.1.1.37; Methyltransferase; Methyltransferase, DNA
Chromosomal Location of Human Ortholog: 6q14
Cellular Component: chromosome, centromeric region; cytoplasm; euchromatin; heterochromatin; nuclear heterochromatin; nuclear matrix; nucleoplasm; nucleus; XY body
Molecular Function: chromatin binding; DNA (cytosine-5-)-methyltransferase activity; DNA binding; identical protein binding; metal ion binding
Biological Process: aging; DNA methylation; DNA methylation during gametogenesis; DNA methylation involved in embryo development; DNA methylation on cytosine; genetic imprinting; methylation-dependent chromatin silencing; mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; neuron differentiation; response to cocaine; response to drug; response to estradiol; response to ethanol; response to ionizing radiation; response to lead ion; response to nutrient levels; response to toxin; response to vitamin A; spermatogenesis; transcription, DNA-dependent
Research Articles on DNMT3A
Similar Products
Product Notes
The Rat DNMT3A dnmt3a (Catalog #AAA3807618) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA3807618 ELISA Kit recognizes Rat DNMT3A. It is sometimes possible for the material contained within the vial of "DNA Methyltransferase 3A (DNMT3A), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
