Rat Cadherin-11 (CDH11) ELISA Kit | CDH11 elisa kit
Rat Cadherin-11 (CDH11) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
Uniprot Description
CDH11: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Interacts with PCDH8. Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Cell adhesion
Chromosomal Location of Human Ortholog: 16q21
Cellular Component: cytoplasm; integral to membrane; plasma membrane
Molecular Function: calcium ion binding
Biological Process: intercellular junction assembly and maintenance; ossification; cell adhesion; homophilic cell adhesion; corticospinal tract morphogenesis; skeletal development
Research Articles on CDH11
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Product Notes
The Rat CDH11 cdh11 (Catalog #AAA7218281) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7218281 ELISA Kit recognizes Rat CDH11. It is sometimes possible for the material contained within the vial of "Cadherin-11 (CDH11), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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